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  1. Research

    Influences of gender on cardiovascular disease risk factors in adolescents with and without type 1 diabetes

    Women with type 1 diabetes (T1D) have a four-fold increased risk for cardiovascular disease (CVD) compared to non-diabetic (non-DM) women, as opposed to double the risk in T1D men compared to non-DM men. It is...

    Talia L. Brown, David M. Maahs, Franziska K. Bishop, Janet K. Snell-Bergeon and R. Paul Wadwa

    International Journal of Pediatric Endocrinology 2016 2016:8

    Published on: 19 April 2016

  2. Research

    An audit of the management of childhood-onset growth hormone deficiency during young adulthood in Scotland

    Adolescents with childhood onset growth hormone deficiency (CO-GHD) require re-evaluation of their growth hormone (GH) axis on attainment of final height to determine eligibility for adult GH therapy (rhGH).

    M. Ahmid, V. Fisher, A. J. Graveling, S. McGeoch, E. McNeil, J. Roach, J. S. Bevan, L. Bath, M. Donaldson, G. Leese, A. Mason, C. G. Perry, N. N. Zammitt, S. F. Ahmed and M. G. Shaikh

    International Journal of Pediatric Endocrinology 2016 2016:6

    Published on: 16 March 2016

  3. Research

    Efficacy of growth hormone replacement on anthropometric outcomes, obesity, and lipids in children with optic nerve hypoplasia and growth hormone deficiency

    Hypopituitarism and obesity are causes of major lifelong morbidity in patients with optic nerve hypoplasia (ONH). Growth hormone deficiency (GHD) affects the majority of children with ONH, though the degree of...

    Carly Stewart, Pamela Garcia-Filion, Cassandra Fink, Anna Ryabets-Lienhard, Mitchell E. Geffner and Mark Borchert

    International Journal of Pediatric Endocrinology 2016 2016:5

    Published on: 2 March 2016

  4. Research

    Increasing incidence of premature thelarche in the Central Region of Denmark - Challenges in differentiating girls less than 7 years of age with premature thelarche from girls with precocious puberty in real-life practice

    Premature thelarche (PT) seems to be increasing and it is difficult to differentiate its early stages from precocious puberty (PP). Clinical and biochemical parameters are warranted to differentiate the two di...

    Mia Elbek Sømod, Esben Thyssen Vestergaard, Kurt Kristensen and Niels Holtum Birkebæk

    International Journal of Pediatric Endocrinology 2016 2016:4

    Published on: 22 February 2016

  5. Research

    Type 1 diabetes through two lenses: comparing adolescent and parental perspectives with photovoice

    Parental support and care-coordination are vital for youth with type 1 diabetes (T1D) in achieving positive health outcomes. Yet, studies are rarely designed to identify factors that influence parent/youth col...

    Ashby Walker, Desmond Schatz, Cathryn Johnson, Janet Silverstein, Shannon Lyles and Henry Rohrs

    International Journal of Pediatric Endocrinology 2016 2016:2

    Published on: 20 January 2016

  6. Research

    Peak cortisol response to corticotropin-releasing hormone is associated with age and body size in children referred for clinical testing: a retrospective review

    Corticotropin-Releasing Hormone (CRH) testing is used to evaluate suspected adrenocorticotropic hormone (ACTH) deficiency, but the clinical characteristics that affect response in young children are incomplete...

    Mary Ellen Vajravelu, Jared Tobolski, Evanette Burrows, Marianne Chilutti, Rui Xiao, Vaneeta Bamba, Steven Willi, Andrew Palladino, Jon M. Burnham and Shana E. McCormack

    International Journal of Pediatric Endocrinology 2015 2015:22

    Published on: 22 October 2015

  7. Research

    Psychosexual development and quality of life outcomes in females with congenital adrenal hyperplasia

    Outcome information regarding females with classical congenital adrenal hyperplasia (CAH) have generally suggested poor quality of life (QoL), general maladjustment, problems regarding sexuality, and decreased...

    Mansi Kanhere, John Fuqua, Richard Rink, Christopher Houk, David Mauger and Peter A. Lee

    International Journal of Pediatric Endocrinology 2015 2015:21

    Published on: 15 October 2015

  8. Case report

    Focal form of congenital hyperinsulinism clearly detectable by contrast-enhanced computed tomography imaging

    The focal form of congenital hyperinsulinism (CHI) is characterized by a cluster of abnormal insulin-oversecreting β cells within a restricted area of the pancreas. Although identification of the focal lesion ...

    Yukiko Hashimoto, Azumi Sakakibara, Rie Kawakita, Yuki Hosokawa, Rika Fujimaru, Tetsuro Nakamura, Hiroko Fukushima, Aiko Igarashi, Michiya Masue, Hironori Nishibori, Nobuyoshi Tamagawa, Akiko Murakami, Kazue Hatake and Tohru Yorifuji

    International Journal of Pediatric Endocrinology 2015 2015:20

    Published on: 15 September 2015

  9. Research

    Noonan syndrome and Turner syndrome patients respond similarly to 4 years’ growth-hormone therapy: longitudinal analysis of growth-hormone-naïve patients enrolled in the NordiNet® International Outcome Study and the ANSWER Program

    Turner syndrome (TS) and Noonan syndrome (NS) are distinct syndromes associated with short stature and other similar phenotypic features. We compared the responses to growth hormone (GH) therapy of TS and NS p...

    Peter A. Lee, Judith L. Ross, Birgitte Tønnes Pedersen, Primoz Kotnik, John A. Germak and Henrik T. Christesen

    International Journal of Pediatric Endocrinology 2015 2015:17

    Published on: 8 September 2015

  10. Case report

    Residual manifestations of hypercortisolemia following surgical treatment in a patient with Cushing syndrome

    Cushing Syndrome is difficult to diagnose, and the comorbidities and persistent late effects of hypercortisolemia after treatment of the primary disease are challenging for the patient and the endocrinologist.

    Sara K. Bartz, Lefkothea P. Karaviti, Mary L. Brandt, Monica E. Lopez, Prakash Masand, Sridevi Devaraj, John Hicks, Lauren Anderson, Maya Lodish, Meg Keil and Constantine A. Stratakis

    International Journal of Pediatric Endocrinology 2015 2015:19

    Published on: 26 August 2015

  11. Case report

    Treatment-resistant pediatric giant prolactinoma and multiple endocrine neoplasia type 1

    Pediatric pituitary adenomas are rare, accounting for <3 % of all childhood intracranial tumors, the majority of which are prolactinomas. Consequently, they are often misdiagnosed as other suprasellar masses s...

    Hoong-Wei Gan, Chloe Bulwer, Owase Jeelani, Michael Alan Levine, Márta Korbonits and Helen Alexandra Spoudeas

    International Journal of Pediatric Endocrinology 2015 2015:15

    Published on: 15 July 2015

  12. Research article

    Association of immunohistochemical markers with premalignancy in Gonadal Dysgenesis

    Gonadal dysgenesis (GD) is associated with increased risk of gonadal malignancy. Determining a patient’s risk and appropriate timing of gonadectomy is challenging, but immunohistochemical markers (IHM) may hel...

    Bonnie McCann-Crosby, Sheila Gunn, E. O’Brian Smith, Lefkothea Karaviti and M. John Hicks

    International Journal of Pediatric Endocrinology 2015 2015:14

    Published on: 15 June 2015

  13. Case report

    Primary ovarian insufficiency in adolescents: a case series

    Primary ovarian insufficiency (POI) is characterized by 4 to 6 months of amenorrhea and elevated serum FSH and LH in females less than 40 years. Ovarian insufficiency is uncommon in pediatrics and typically re...

    Julia Pederson, Rajiv B Kumar, Paula J Adams Hillard and Laura K Bachrach

    International Journal of Pediatric Endocrinology 2015 2015:13

    Published on: 15 May 2015

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International Journal of Pediatric Endocrinology is affiliated with the Asia Pacific Paediatric Endocrine Society (APPES)