Higher fibre and lower fat intake is associated with better vascular function in children with type 1 diabetes
© Toome et al; licensee BioMed Central Ltd. 2015
Published: 28 April 2015
Children with type 1 diabetes (T1D) might not consume a healthy diet. A healthy diet is associated with reduced risk of cardiovascular disease (CVD) in adults, but there is no data evaluating the association between diet composition and early markers of CVD in T1D children. We aimed to investigate the macro/micronutrient intakes of T1D children and the relationship with vascular function.
The Australian Child and Adolescent Eating Survey (ACAES–version1.2) Food Frequency questionnaire was administered to 77 T1D children (aged 14±2.3 years, 37 males, BMI z-score 0. ±0.6) participating in an RCT, obtaining in-depth macro/micronutrient intake. Vascular function was measured by Flow Mediated Dilatation (FMD) and Glyceryl Trinitrate Mediated Dilatation (GTN). Pearson’s correlation and multivariate regression analysis determined dietary predictors of vascular function.
Children had diabetes duration 5.7±3.9 years, median HbA1c 8.7(range: 6.3-14)% and insulin dose 0.8±0.2 units/kg/day. 37 children used CSII.
Independent predictors of GTN
Higher fibre and lower total fat intake, is associated with better vascular function in T1D children. This is the first evidence that diet composition may reduce the risk of CVD in children with T1D in addition to improving diabetes control.
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