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Table 2 Summary of differences of log transformed data between treatment pairs

From: Differential effects of hydrocortisone, prednisone, and dexamethasone on hormonal and pharmacokinetic profiles: a pilot study in children with congenital adrenal hyperplasia

Drug pair

ACTH

Androstenedione

17-OHP

Difference (95 % CI)

p-value

Difference (95 % CI)

p-value

Difference (95 % CI)

p-value

DEX-HC

−0.55 (−0.99, −0.12)

0.016**

−0.64 (−1.15, −0.14)

0.016**

−1.59 (−1.94, −1.23)

< 0.001**

DEX-PDN

−0.90 (−1.33, −0.47)

< 0.001**

−0.90 (−1.40, −0.40)

0.002**

−2.44 (−2.80, −2.09)

< 0.001**

HC- PDN

−0.35 (−0.78, 0.09)

0.110

−0.26 (−0.76, 0.25)

0.293

−0.86 (−1.21, −0.50)

< 0.001**

  1. Values are expressed as the difference between drug groups (first drug minus the second drug) with 95 % confidence interval (CI)
  2. ** Significant p-value is ≤ 0.017
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International Journal of Pediatric Endocrinology

ISSN: 1687-9856

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