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Table 2 Treatment effect of GH on anthropometric and body composition outcomes

From: Efficacy of growth hormone replacement on anthropometric outcomes, obesity, and lipids in children with optic nerve hypoplasia and growth hormone deficiency

 

Unadjusted

Adjusteda

 

βb ± SE

95 % CI

p-value

βb ± SE

95 % CI

p-value

Stature SDS

0.98 ± 0.43

0.14, 1.82

0.022

0.96 ± 0.44

0.09, 1.82

0.030

Weight SDS

0.55 ± 0.48

−0.39, 1.50

0.251

0.83 ± 0.40

0.04, 1.62

0.040

BMI SDS

−0.03 ± 0.57

−1.15, 1.09

0.959

0.40 ± 0.43

−0.44, 1.25

0.349

Weight-for-Stature SDS

−0.12 ± 0.50

−1.11, 0.87

0.808

0.26 ± 0.35

−0.44, 0.95

0.468

Body Fat (%)

−6.1 ± 2.8

−11.5, −0.6

0.030

−4.3 ± 2.3

−8.8, 0.1

0.057

  1. aAdjusted for overweight status at baseline (normal/underweight/overweight)
  2. bβ represents regression coefficient, interpreted as the average response [increase or decrease (−)] to GH replacement compared to no replacement