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Table 2 Treatment effect of GH on anthropometric and body composition outcomes

From: Efficacy of growth hormone replacement on anthropometric outcomes, obesity, and lipids in children with optic nerve hypoplasia and growth hormone deficiency

  Unadjusted Adjusteda
  βb ± SE 95 % CI p-value βb ± SE 95 % CI p-value
Stature SDS 0.98 ± 0.43 0.14, 1.82 0.022 0.96 ± 0.44 0.09, 1.82 0.030
Weight SDS 0.55 ± 0.48 −0.39, 1.50 0.251 0.83 ± 0.40 0.04, 1.62 0.040
BMI SDS −0.03 ± 0.57 −1.15, 1.09 0.959 0.40 ± 0.43 −0.44, 1.25 0.349
Weight-for-Stature SDS −0.12 ± 0.50 −1.11, 0.87 0.808 0.26 ± 0.35 −0.44, 0.95 0.468
Body Fat (%) −6.1 ± 2.8 −11.5, −0.6 0.030 −4.3 ± 2.3 −8.8, 0.1 0.057
  1. aAdjusted for overweight status at baseline (normal/underweight/overweight)
  2. bβ represents regression coefficient, interpreted as the average response [increase or decrease (−)] to GH replacement compared to no replacement