Table 1 Urinary steroid ratios and the number of cases with an abnormal ratio
Ratio | Cases analysed out of 93 | Cases >95 th percentile | Cases of suspected steroid disorder with ratio >95 th percentile (% of those with ratio >95 th percentile) | Sensitivity | Specificity | Positive predictive value | Negative predictive value |
|---|---|---|---|---|---|---|---|
17HP/(THE + THF + 5αTHF) | 93 (100%) | 18 | 4 (22%) | 100% | 84% | 22% | 100% |
PT/(THE + THF + 5αTHF) | 92 (99%) | 16 | 4 (25%) | 100% | 86% | 25% | 100% |
PTONE/(THE + THF + 5αTHF) | 61 (65%) | 11 | 5 (45%) | 100% | 89% | 45% | 100% |
THS/(THE + THF + 5αTHF) | 92 (99%) | 23 | 4(17%) | 100% | 78% | 17% | 100% |
DHEA/(THE + THF + 5αTHF) | 90 (96%) | 12 | 2 (17%) | 100% | 90% | 17% | 100% |
(17HP + PT)/(An + Et) | 85 (90%) | 6 | 2 (33%) | 100% | 95% | 33% | 100% |
(THF + 5αTHF)/THE | 93 (100%) | 7 | 1 (14%) | 100% | 93% | 14% | 100% |
THE/(THF + 5αTHF) | 93 (100%) | 9 | 1 (11%) | 100% | 91% | 11% | 100% |
(An + Et)/(THE + THF + 5αTHF) | 89 (95%) | 6 | 1 (17%) | 100% | 94% | 17% | 100% |
Et/An | 84 (89%) | 6 | 2 (33%) | 100% | 95% | 33% | 100% |
THF/5αTHF | 93 (100%) | 10 | 2 (20%) | 100% | 91% | 20% | 100% |
THB/5αTHB | 86 (91%) | 6 | 1 (17%) | 100% | 94% | 17% | 100% |