Volume 2015 Supplement 1

Abstracts from the 8th APPES Biennial Scientific Meeting

Open Access

Risk factors for idiopathic central precocious puberty of girls in Fujian province

  • Ruimin Chen1,
  • Chunyan Cai2,
  • Zhijian Hu1,
  • Xianquan Lin1,
  • Yunfei Li1,
  • Ying Zhang1,
  • Xiaohong Yang1 and
  • Xin Yuan1
International Journal of Pediatric Endocrinology20152015(Suppl 1):P94

https://doi.org/10.1186/1687-9856-2015-S1-P94

Published: 28 April 2015

Keywords

precocious puberty risk factors Logistic Regression analysis

Objective

This study aimed to investigate the potential risk factors of idiopathic central precocious puberty (ICPP) girls in Fujian province.

Methods

A case-control study was conducted in 566 girls who were diagnosed with ICPP at endocrinology department and 547 healthy girls for routine physical examination in Fuzhou Children’s Hospital of Fujian from October 2011 to October 2013. Parents were asked to fulfill the questionnaires on children’s diets, behaviors, parents and family conditions, and Logistic regression analysis was conducted for risk factors.

Results

Chi-square test showed that 23 variables had significant statistically difference. Logistic regression analysis indicated that some variables were entered the final model: mother's age at menarche were older than 13 years (OR=0.278, 95%CI: 0.201,0.384), intaking organic fruits (OR=0.316, 95%CI: 0.157,0.634), daily exercise time(OR=0.609, 95%CI: 0.490,0.758), intaking ordinary vegetables (OR=1.275, 95%CI: 1.095,1.485), intaking general livestock (OR=1.364, 95%CI: 1.199,1.551), BMI(OR=1.599, 95%CI: 1.365,1.874), income of parents (OR=1.671, 95%CI: 1.317,2.120), heavy study burden (OR=1.818, 95%CI: 1.121,2.948), intaking instant food(OR=2.990, 95%CI: 1.241,7.203), intaking nourishment (OR=3.736, 95%CI: 2.063,6.765), using adult cosmetics (OR=5.284, 95%CI: 3.240,8.618). Among the variables, mother's age at menarche were older than 13 years, intaking organic fruit and doing more exercise for a long time were demonstrated to be the protective factors for ICPP, and others were risk factors.

Conclusion

There were many factors related to ICPP girls in Fujian province, such as mother’s age at menarche, diet and behaviors, BMI, parental income, and heavy study burden.

Authors’ Affiliations

(1)
Fuzhou Children’s Hospital of Fujian
(2)
Fujian Medical University

Copyright

© Chen et al; licensee BioMed Central Ltd. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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