- Poster presentation
- Open access
- Published:
Test on kisspeptin levels in girls with idiopathic central precocious puberty and its significance
International Journal of Pediatric Endocrinology volume 2015, Article number: P91 (2015)
Aims
This paper is aimed to explore the significance of plasma kisspeptin level in diagnosis and therapeutic evaluation through the detection of kisspeption level of girls diagnosed with idiopathic central precocious puberty (ICPP) before treatment and after 6-months of treatment and girls with simple premature thelarche (PT).
Methods
A total of 70 girls including 24 girls diagnosed with ICPP, 21 girls with PT and 25 normal girls were enrolled. ELISA was adopted to detect plasma kisspeptin level.
Results
The kisspeptin level of ICPP group before treatment (1.80±0.13ng/ml)was higher than those of other groups with significantly statistic difference. The kisspeptin level of ICPP group after 6-months of treatment (1.49±0.21ng/ml) was significantly lower than those before treatment (P<0.05).
Conclusions
We can conclude that plasma kisspeptin level is related with initiation of pubertal development, and it can be served as important parameter in ICPP diagnosis and therapeutic effect evaluation.
Author information
Authors and Affiliations
Rights and permissions
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
About this article
Cite this article
Yang, Y., Xiong, Xy., Yang, L. et al. Test on kisspeptin levels in girls with idiopathic central precocious puberty and its significance. Int J Pediatr Endocrinol 2015 (Suppl 1), P91 (2015). https://doi.org/10.1186/1687-9856-2015-S1-P91
Published:
DOI: https://doi.org/10.1186/1687-9856-2015-S1-P91