Table 1 Characteristics of the 24 adolescent males at onset of rhGH or rhGH + Anastrazole administration and historical controls
|  | GH alone | GH + Anastrazole | Historicals controls |
|---|---|---|---|
N | 12 | 12 | 17 |
Father’s height |  |  |  |
 cm | 168.5 ± 4.9 | 168.9 ± 3.6 | 169.2 ± 4.1 |
 SDS | - 1.2 ± 0.8 | - 1.1 ± 0.6 | −1.1 ± 0.8 |
Mother’s height |  |  |  |
 cm | 157.8 ± 5.8 | 156.4 ± 6 | 157.9 ± 5 |
 SDS | - 1.2 ± 1 | - 1.2 ± 1.1 | −1.2 ± 1 |
Birth length (cm) | 48.3 ± 1 | 48.2 ± 1.2 | 48.4 ± 1.2 |
Age (yrs) | 15.2 ± 1.1 | 15.2 ± 0.8 | 15.1 ± 0.8 |
Height | Â | Â | Â |
 cm | 156.3 ± 2.9 | 155.9 ± 4 | 156.1 ± 3.5 |
 SDS | - 1.70 ± 1 | - 1.70 ± 0.7 | −1.67 ± 0.8 |
Weight (kg) | 49.8 ± 4 | 48 ± 6 | 49.9 ± 4 |
Testes volume (ml) | 22.4 ± 8 | 22.2 ± 5 | 22 ± 5 |
Serum testosterone (ng/ml) | 5.5 ± 0.9 | 5.6 ± 0.9 | 5.5 ± 0.8 |
Bone age at hand (yrs) | 14.6 ± 0.6 | 14.5 ± 0.8 | 14.6 ± 0.7 |
Knee score* | 2.8 ± 0.7 | 2.8 ± 0.4 | 2.7 ± 0.4 (N = 10) |
IGF1 (SDS) | - 0.5 ± 0.4 | - 0.3 ± 0.6 | −0.4 ± 0.6 (N = 10) |