Table 1 Protein spot displaying intensity differences (p < 0.05) between obese children (OB) and controls (C) before FDR analysis
Spot | Spot intensity in OB | MS | MS | MS | MS -MS | MS-MS | MS-MS | Identification |
|---|---|---|---|---|---|---|---|---|
Significance level | Score/Cut-off | Matched fragments | Sequence coverage (%) | Score/Cut-off | Matched (Significant) fragments | Sequence coverage (%) | ||
1809 | Upregulated, p < 0.05 | 68/66 | 15 | 26 | 45/40 | 2 (1) | 6 | Alpha 1B acid glycoprotein |
2201 | Downregulated, p < 0.01 | 115/66 | 12 | 50 | 98/41 | 9 (6) | 40 | Apolipoprotein A1 |
2203 | Downregulated, p < 0.05 | 44/66 | 3 | -- | 102/41 | 3(3) | 6 | Clusterin (Apolipoprotein J) |
2301 | Downregulated, p < 0.05 | 56/66 | 7 | -- | 95/41 | 5(4) | 23 | Clusterin (Apolipoprotein J) |
2306 | Upregulated, p < 0.05 | 75/66 | 7 | 30 | 71/41 | 6(2) | 17 | Haptoglobin |
3201 | Downregulated, p < 0.05 | 137/66 | 16 | 59 | 81/41 | 8(4) | 33 | Apolipoprotein A1 |
3202 | Downregulated, p < 0.01 | 71/66 | 8 | 34 | 81/41 | 6(4) | 25 | Apolipoprotein A1 |
3307 | Upregulated, p < 0.05 | 91/66 | 7 | 36 | 61/58 | 3(1) | 6 | Haptoglobin |
4401 | Downregulated, p < 0.05 | 68/66 | 6 | 83 | 95/59 | 2(2) | 28 | Transthyretin chain A |
5603 | Downregulated, p < 0.05 | 71/66 | 6 | 11 | 79/59 | 3(1) | 6 | Haptoglobin |
5604 | Downregulated, p < 0.01 | 82/66 | 11 | 49 | 84/58 | 2(1) | 4 | Haptoglobin |
6203 | Downregulated, p < 0.05 | 127/66 | 17 | 65 | 76/58 | 6(3) | 29 | Apolipoprotein A1 |
7102 | Upregulated, p < 0.01 | 55/66 | 8 | -- | 64/56 | 2(1) | 13 | Haptoglobin (alpha2) |
7201 | Downregulated, p < 0.01 | 106/66 | 16 | 66 | 76/59 | 3(2) | 13 | Apolipoprotein A1 |
7503 | Downregulated, p < 0.05 | 53/66 | 5 | -- | 64/58 | 2(2) | 7 | Vitamin D binding protein |
8102 | Upregulated, p < 0.01 | 68/66 | 5 | 20 | 70/57 | 3(1) | 8 | Haptoglobin (alpha2) |
9101 | Upregulated, p < 0.05 | 49/66 | 3 | -- | 105/55 | 1(1) | 4 | Haptoglobin (alpha2) |