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Table 4 Hormonal levels according to CAG/GGC haplotypes

From: Hormonal profile and androgen receptor study in prepubertal girls with hypertrichosis

 

Cases (n)

Controls (n)

Hap 1-2

Hap 3-5

Hap 1-2

Hap 3-6

Age (years)

5.9 ± 2.2 (13)

59 ± 1.(23)

7.0 ± 1 8 (4)

6.0 ± 1.5 (25)

Hypertrichosis score

16.0 ± 3.3 (13)&

17.1 ± 3.2 (23)&

1.8 ± 1.0 (4)

3.5 ± 2.0 (25)

Follicle number per ovary

4.9 ± 1.5 (9)

5.0 ± 3.0 (17)

3.3 ± 1.0 (3)

3.8 ± 1.4 (15)

LH (mUI/mL)

0.5 ± 0.4 (11)

0.4 ± 0.1 (19)&

0.5 ± 0.1 (4)

0.5 ± 0.2 (22)

FSH

2,0 ± 1.0 (11)

2.0 ± 1.1 (19)

2.4 ± 0.8 (4)

2.9 ± 3.2 (22)

Testosterone (ng/mL)

0.1 ± 0.06 (11)*

0.2 ± 0.06 (23)

02 ± 0.08 (4)

0.1 ± 0.06 (23)

Androstenedione (ng/mL)

0.2 ± 0.6 (11)*

0.4 ± 0.49 (20)

0.2 ± 0.08 (4)

0.2 ± 0.16 (22)

DHEAS (ng/mL)

38 ± 39 (11)*

161 ± 190 (22)

81 ± 82 (4)

98 ± 86 (23)

17OH progesterone (ng/mL)

0.5 ± 0.2 (12)

0.7 ±0.4 (20)

04 ± 0.15 (4)*

0.8 ± 0.5 (22)

Estradiol

8.74 ± 6.5 (11)

749 ± 4.2 (19)

7.45 ± 3.7 (4)

8.38 ± 4.7 (22)

SHBG (nmoL/L)

77.2 ± 16.7 (12)

68.2 ± 15.6 (19)&

79.3 ± 18 (4)

82.4 ± 15 (22)

FAI

0.54 ± 0.36 (11)

0.98 ± 0.77 (22)&

0.64 ± 0.18 (41)

0.62 ± 0.39 (23)

AMH (pmol/L)

41.6 ± 24.7 (12)*

23.8 ± 17.9 (20)

30.1 ± 5.9 (4)

22.4 ± 10.2 (22)

Inhibin B (pg/mL)

18.9±18 (12)&

14 ± 11 (20)

8.3 ± 3.3 (4)

12 ± 4.1 (22)

  1. Values are mean ± DS. *P<0.03 hap 1–2 versus hap 3–6 in cases or controls; &P<0.05 cases vs controls. Krustal Wallis Test.