Hormonal profile and androgen receptor study in prepubertal girls with hypertrichosis

Table 3 Distribution of combination CAG/GGC haplotypes

Hap N°	CAG/GGC haplotypes definition	Girls		Total
Hap N°	CAG/GGC haplotypes definition	Hypertrichosis	Controls	(n)
1	<22CAG + 17/17GGC	12 (28.6%)	4 (13.8%)	16
2	<14CAG + 17/18GGC	3 (7.1%)	0 (0%)	3
3	(≥18 and < 22)CAG + 17/18GGC	3 (7.1%)	6 (20.7%)	9
4	<22CAG + (<17 and/or >17)GGC	5 (11.9%)	6 (20.7%)	11
5	≥22/22CAG + (17 and/or 18)GGC	18 (42.9%)	13 (44.8%)	31
	Total (n)	41	29	70

One girl with hypertrichosis had a genotype: 20/27 CAG and 14/17 GGC and therefore did not classify in any of this haplotypes.
The prevalence of the most sensitive combinations (1 and 2) was significantly higher in girls with hypertrichosis than in controls (37.5% vs 13.8% P = 0.04 Chi² test).

ISSN: 1687-9856