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Table 3 Distribution of combination CAG/GGC haplotypes

From: Hormonal profile and androgen receptor study in prepubertal girls with hypertrichosis

Hap N° CAG/GGC haplotypes definition Girls Total
Hypertrichosis Controls (n)
1 <22CAG + 17/17GGC 12 (28.6%) 4 (13.8%) 16
2 <14CAG + 17/18GGC 3 (7.1%) 0 (0%) 3
3 (≥18 and < 22)CAG + 17/18GGC 3 (7.1%) 6 (20.7%) 9
4 <22CAG + (<17 and/or >17)GGC 5 (11.9%) 6 (20.7%) 11
5 ≥22/22CAG + (17 and/or 18)GGC 18 (42.9%) 13 (44.8%) 31
  Total (n) 41 29 70
  1. One girl with hypertrichosis had a genotype: 20/27 CAG and 14/17 GGC and therefore did not classify in any of this haplotypes.
  2. The prevalence of the most sensitive combinations (1 and 2) was significantly higher in girls with hypertrichosis than in controls (37.5% vs 13.8% P = 0.04 Chi2 test).