Growth hormone significantly increases the adult height of children with idiopathic short stature: comparison of subgroups and benefit

Table 6 Analysis of Intent to Treat to Adult Height Treatment Response with rhGH

	Number	Years observation (Mean SDS ± SD)	Growth rate cm/yr (Mean SDS ± SD)	Δ Height SDS (Mean SDS ± SD)
Males pretreatment
Lost to follow-up	22	2.46 ± 1.87	4.29 ± 1.42	-0.31 ± 0.48
Treated to AH	50	2.42 ± 1.37	4.00 ± 1.02	-0.33 ± 0.54
			p, 0.426	p, 0.902
On treatment with rhGH
Before puberty
Lost to follow - up	21	1.20 ± 1.02	7.92 ± 0.94	0.53 ± 0.41
Treated to AH	41	1.83 ± 1.51	8.31 ± 1.44	0.71 ± 0.57
			p, 0.207	p, 0.179
During puberty
Lost to follow - up	7	1.34 ± 0.75	9.09 ± 2.24	0.50 ± 0.28
Treated to AH	50	2.05 ± 1.04	8.31 ± 1.74	0.72 ± 0.48
			p, 0.404	p, 0.116
Females pretreatment
Lost to follow-up	5	2.76 ± 1.54	3.78 ± 1.40	-0.56 ± 0.49
Treated to AH	17	3.71 ± 2.34	4.56 ± 0.71	-0.50 ± 0.37
			p, 0.293	p, 0.810
On treatment with rhGH
Before puberty
Lost to follow - up	5	1.01 ± 0.25	8.06 ± 1.36	0.48 ± 0.32
Treated to AH	10	1.20 ± 0.51	8.94 ± 0.92	0.58 ± 0.27
			p, 0.241	p, 0.593
During puberty
Lost to follow - up	2	1.02 ± 0.03	9.34 ± 2.07	0.72 ± 0.58
Treated to AH	20	1.94 ± 0.97	7.30 ± 1.77	1.05 ± 0.45
			p, 0.382	p, 0.559

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