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Table 11 NFSS & FSS Adult Height Gain of Controls and Treated Subjects SDS (95% CI)

From: Growth hormone significantly increases the adult height of children with idiopathic short stature: comparison of subgroups and benefit

   GH Dosage Adult height gain of controls untreated NFSS to FSS Difference Adult height gain of treated subjects NFSS to FSS Difference
Published study No. mg/kg/wk Mean SDS (95% CI) SDS p Mean SDS (95% CI) SDS p
Wit et al. NFSS [9] 36 0.32 to 0.14 0.8 (0.62 to 0.98) 0.5 SDS p <0.01 1.50 (1.23 to 1.77) 0.7 SDS p <0.05
Wit et al. [9] FSS 5 0.32 to 0.27 0.3 (-0.05 to 0.65) 0.80 (0.06 to 1.54)
Albertsson-Wikland et al. NFSS [3] 48 0.47 0.5 (0.23 to 0.77) 0.6 SDS p <0.05 1.40 (1.17 to 1.63) 0.5 SDS p < 0.05
Albertsson-Wikland et al. [3] FSS 14 0.47 -0.1 (-0.79 to 0.59) 0.90 (0.44 to 1.36)
    Adult height   Adult height gain  
Our Study NFSS (treated) 63 0.32 (0.03) -0.56 (-0.72 to -0.40) 0.52 SDS p < 0.01 2.06 (1.87 to 2.25) 0.55 SDS p <0.001
Our Study FSS (treated) 25 0.32 (0.03) -1.08 (-1.41 to -0.75) 1.51 (1.24 to 1.78)