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Table 1 Mineral homeostasis and DXA data at baseline and 1 year

From: Six monthly intravenous zoledronic acid in childhood osteoporosis

 

Baseline

1 year

Calcium (mmol/L)

2.38 (2.35-2.44)

2.36 (2.28-2.42)

Alkaline phosphatase (U/L)

188 (143-271)

148.5 (127.25-205.5)*

Osteocalcin (nmol/L)

7.9 (4.35-11.35)

2.5 (1.1-3.95)*

25-OH-VitD (nmol/L)

75 (67-94)

76 (57.5-86)

Parathyroid hormone (pmol/L)

3.5 (2.3-4.1)

3.7 (2.9-5.4)

Total body aerial BMD Z-score

-0.56 (-1.7 to 0.35)

-0.03 ( -1.13 to 0.86)*

L2-4 aerial BMD Z-score

-1.73 (-2.43 to -0.96)

-0.37 (-1.44 to 0.09)*

Bone mineral content for lean tissue mass Z-score

-1.68 (-2.51 to -0.60)

-0.10 (-0.9 to 1.35)*

  1. Values represent median (interquartile range), asterisk represents p<0.05 compared to baseline