From July 2011 until now, we have 5 cases of OI in our hospital; all of them were type 3. The youngest was 3 days old and the oldest was 9 years old, all of them were male. These patients have well defined phenotypes, including extremely short stature, progressive limb and spine deformities. We found respiratory problems in 2 patients, a 3 days and 2 months old baby. Diagnosis was based on clinical and radiology examination (bone survey). All of them came from low social economic status, and only 2 patients had government health insurance. The major problem in managing OI patients is the treatment, intravenous pamidronate was not available in our province therefore we must order it from our national referral hospital in Jakarta. Moreover, the price was expensive, and it was not covered by health insurance. Only 1 patient received this treatment and only for 1 cycle. One patient died at home because of respiratory problem. BMD or DXA was also not available in our province.