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  • Open Access

Adrenal cortex tumors: clinical features and laboratory finding

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International Journal of Pediatric Endocrinology20132013 (Suppl 1) :P110

  • Published:


  • Carcinoma
  • Hypertension
  • Internal Medicine
  • Adenocarcinoma
  • Testosterone

The adrenal cortex tumors (ACT) include both malignant adrenal cortex cancers and benign masses that can be either secreting, of one of the hormones normally produced in the adrenal cortex or non-secretory. We describe clinical features and laboratory finding of patients with adrenal cortex tumors. This is a case series report. 29 cases of childhood with adrenal cortex tumors treated at the Vietnam National Hospital of Pediatrics in a period of 1995–2011 have been reviewed in detail the presenting features and laboratory. The study recruited 15 boys and 14 girls. The median age at diagnosis was 4.97 ± 3.61 yrs (range, 20 days to 14 yrs); 19 patients were younger than 5 yrs. Hypertension and cushingoid features were common in patients (62%, 58.6%), virilization was presenting feature in 44.8% of the group. An abdominal mass was palpable in 20.7 % of the patients. High level of testosterone was common in patients (94.1%). 30% of the patients had hypercotisonemia. All tumors were unilateral; the right adrenal glands predominated over left (1.9 :1). 62.5 % tumors over 4 cm. 22 patients had received operation to remove the tumors: 11 carcinoma, 2 adenocarcinoma. In conclusion, high percentage of patients had malignant tumors among ACT operated patients.

Authors’ Affiliations

National Hospital of Pediatrics, Hanoi, Vietnam
Hanoi Medical University, Hanoi, Vietnam


© Ngoc et al; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.