Table 7 Comparison of first-year growth for patients with IGHD who had all the characteristics of the best responders with those predicted to be poor responders
Variable | Predicted best first-year HV SDS criterion n = 28 | Predicted poor first-year HV SDS criterion n = 29 |
|---|---|---|
Baseline height SDS | < −3 | > −2.5 |
Baseline BMI SDS | > −0.5 | < −1 |
Pre-treatment HV (cm/yr) | < 3.5 | > 4 |
Baseline height SDS minus mid-parental target height SDS | > 3 | < 2 |
Maximum stimulated GH (ng/mL) | ≤ 4 | ≥ 7 |
Female (n)/male (n) | 5/23 | 7/22 |
Mean (SD) | Mean (SD) | |
Baseline age (yr) | 6.5 (1.8) | 6.8 (2.0) |
Baseline height SDS | −4.1 (0.7) | −1.9 (0.3) |
Baseline BMI SDS | 0.5 (0.8) | −1.5 (0.5) |
Pre-treatment HV (cm/yr) | 1.9 (1.0) | 6.2 (1.9) |
Baseline height SDS minus mid-parental target height SDS | 4.2 (0.7) | 1.4 (0.5) |
Maximum stimulated GH (ng/mL) | 1.9 (1.0) | 8.6 (0.8) |
First-year HV (cm/yr) | 13.1 (2.7) | 9.1 (2.3) |
First-year Bakker HV SDS | 1.21 (1.3) | −0.51 (0.9) |
Second-year HV (cm/yr) | 8.5 (2.0) | 7.3 (1.4) |
Second-year Bakker HV SDS | 0.33 (1.3) | −0.37 (0.8) |