|
Subjects
|
DXA Controls
|
---|
Baseline: n=29 (24 boys)
|
n=241 (105 boys)
|
---|
6 months: n=23 (19 boys)
|
---|
36 months n=14 (12 boys)
|
---|
LS mean
|
Compared to DXA controls
|
LS mean
|
Comparator
|
---|
Lean tissue (kg)
|
Baseline
|
20.82
|
p=0.22
|
21.36
| |
6 months
|
20.79
|
p=0.14
|
21.51
|
36 months
|
20.00
|
p=0.007
|
21.72
|
BMC (kg)
|
Baseline
|
1.053
|
p=0.04
|
1.001
| |
6 months
|
1.052
|
p=0.13
|
1.011
|
36 months
|
1.050
|
p=0.46
|
1.024
|
BMD (kg/m2)
|
Baseline
|
0.891
|
p<0.0001
|
0.849
| |
6 months
|
0.889
|
p=0.0002
|
0.851
|
36 months
|
0.889
|
p=0.006
|
0.854
|
Total fat (kg)
|
Baseline
|
6.28
|
p=0.24
|
5.55
| |
6 months
|
4.84
|
p=0.25
|
5.62
|
36 months
|
5.35
|
p=0.69
|
5.71
|
Central/total fat
|
Baseline
|
0.421
|
p<0.0001
|
0.349
| |
6 months
|
0.390
|
p=0.0009
|
0.350
|
36 months
|
0.383
|
p=0.047
|
0.352
|
- LS Mean: Least squares mean and p values compared to DXA controls using general linear model controlling for effects of age, sex and height.
- DXA: Dual-energy X-ray absorptiometry.
- Statistically significant p-values are given in bold type.