Time period (months: mean ± SD)

Pretreatment

06 months

612 months

1224 months

2436 months


(16.6 ± 9.4)

(6.3 ± 1.5)

(7.3 ± 2.0)

(11.4 ± 2.1)

(10.9 ± 2.5)



n=11

n=30

n=30

n=28

n=24


Height velocity (cm/year)

6.5 ± 1.1

4.3 ± 1.9

4.5 ± 1.3

4.7 ± 1.2

5.3 ± 1.2

Weight velocity (kg/year)

2.7 ± 1.8

−1.5 ± 2.8

3.2 ± 3.1

2.9 ± 2.3

4.1 ± 2.3

Change in BMI/year

0.08 ± 0.86

−2.09 ± 1.89

0.81 ± 1.74

0.45 ± 1.05

0.83 ± 0.95

Δ Height Zscore/year

−0.04 ± 0.17

−0.32 ± 0.38***

−0.22 ± 0.21***

−0.11 ± 0.19**

−0.02 ± 0.17

Δ Weight Zscore/year

−0.09 ± 0.36

−1.04 ± 0.74***

0.03 ± 0.63

−0.13 ± 0.27*

0.06 ± 0.29

Δ BMI Zscore/year

−0.08 ± 0.44

−1.29 ± 0.94***

0.26 ± 0.96

−0.10 ± 0.39

0.12 ± 0.43

 *p<0.05; **p<0.01; ***p<0.001 for the change in Zscore over the time period using single sample ttests against a test value of zero.
 Statistical analysis was applied to the changes in Zscores only and used single sample ttests with a test value of zero.