Time period (months: mean ± SD)
|
Pre-treatment
|
0-6 months
|
6-12 months
|
12-24 months
|
24-36 months
|
---|
(16.6 ± 9.4)
|
(6.3 ± 1.5)
|
(7.3 ± 2.0)
|
(11.4 ± 2.1)
|
(10.9 ± 2.5)
|
---|
|
n=11
|
n=30
|
n=30
|
n=28
|
n=24
|
---|
Height velocity (cm/year)
|
6.5 ± 1.1
|
4.3 ± 1.9
|
4.5 ± 1.3
|
4.7 ± 1.2
|
5.3 ± 1.2
|
Weight velocity (kg/year)
|
2.7 ± 1.8
|
−1.5 ± 2.8
|
3.2 ± 3.1
|
2.9 ± 2.3
|
4.1 ± 2.3
|
Change in BMI/year
|
0.08 ± 0.86
|
−2.09 ± 1.89
|
0.81 ± 1.74
|
0.45 ± 1.05
|
0.83 ± 0.95
|
Δ Height Z-score/year
|
−0.04 ± 0.17
|
−0.32 ± 0.38***
|
−0.22 ± 0.21***
|
−0.11 ± 0.19**
|
−0.02 ± 0.17
|
Δ Weight Z-score/year
|
−0.09 ± 0.36
|
−1.04 ± 0.74***
|
0.03 ± 0.63
|
−0.13 ± 0.27*
|
0.06 ± 0.29
|
Δ BMI Z-score/year
|
−0.08 ± 0.44
|
−1.29 ± 0.94***
|
0.26 ± 0.96
|
−0.10 ± 0.39
|
0.12 ± 0.43
|
- *p<0.05; **p<0.01; ***p<0.001 for the change in Z-score over the time period using single sample t-tests against a test value of zero.
- Statistical analysis was applied to the changes in Z-scores only and used single sample t-tests with a test value of zero.