Table 1 Baseline patient demographics (n = 30)
From: Fulvestrant treatment of precocious puberty in girls with McCune-Albright syndrome
Mean age ± SD (range) | 5.86 years ± 1.8 (1.7-8.5) |
|---|---|
Ethnicity | |
White | 26 (87%) |
Biracial | 2 (7%) |
Black | 1 (3%) |
Hispanic | 1 (3%) |
Polyostotic fibrous dysplasia (n) | 21 (70.0%) |
Café au lait spots (n) | 24 (80.0%) |
Confirmed Gsα mutation (n) | 7 (23.3%) |
Vaginal bleeding during 6 months pre-treatment (n) | 23 (76.7%) |
Median Tanner Stage for breasts (range) | III (I-IV) |
Median Tanner Stage for pubic hair (range) | I (I-IV) |
Mean growth velocity Z-score ± SD during 6 months prior to study | 2.35 ± 3.3 |