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Table 3 Study group baseline pubertal hormone levels. Observed range for each study group is shown, as is 5th–95th percentile reference range of healthy prepubertal volunteers [20].

From: LH Dynamics in Overweight Girls with Premature Adrenarche and Slowly Progressive Sexual Precocity

GROUP LH (IU/L) FSH (IU/L) E2 (pg/mL) Total T (ng/dL) Free T (pg/mL) SHBG (nM) A'dione (ng/dL) 17OHP (ng/dL) PROG (ng/dL) DHEAS (g/dL)
PA           
Mean 0.15 1.7 6.4 15.6 3.7 23 42.0 35.9 25.0 67
SEM 0.00 0.2 0.4 2.5 0.6 6.1 7.9 5.4 0.0 12
Range 0.15 0.9–2.8 5.0–8.0 10–26 2.0–6.0 8–54 25–80 25–64 25 28–103
SPPOPA           
Mean 0.15 1.6 9.6 16.2 4.8 17 45.2 26.2 25.3 62
SEM 0.00 0.5 2.5 2.5 1.2 3.9 3.9 1.2 0.3 10
Range 0.15 0.9–2.9 5.0–19 10–21 2.0–8.0 2–23 36–59 25–31 25–26 35–87
OW-PUB           
Mean 2.1 3.7 24.8 27.4 6.6 24 74.1 48.4 25.4 40
SEM 0.71 0.8 6.5 4.5 1.1 3.2 15.2 8.8 0.4 7.4
Range 0.15–5.8 0.5–6.2 5.0–53 14–47 4–10 9–40 29–149 25–91 25–28 11–72
Prepubertal           
Reference Range 0.15 0.42.4 5.08.0 10 2.0 1658 2543 2552 25 542
  1. -values versus OW-PUB: .
  2. E2 (estradiol); T (testosterone); SHBG (sex hormone binding globulin); A'dione (androstenedione); 17OHP (17-hydroxyprogesterone); PROG (progesterone); DHEAS (dehydroepiandrosterone sulfate).
  3. Conversions to SI units: E2  3.61  pmol/L; Testosterone  0.0347  nmol/L; Free testosterone  3.47  pmol/L; A'dione  0.0349  nmol/L; 17OHP  0.0303  nmol/L; PROG  0.318  nmol/L; DHEAS  0.0271 mol/L.