Table 1 Baseline demographics.
GHD | MPHD | TS | SGA | NS | ISS | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean (SD) |
| Mean (SD) |
| Mean (SD) |
| Mean (SD) |
| Mean (SD) |
| Mean (SD) | |
Gender, M/F | 2,918/952 | 220/135 | 0/382 | 224/136 | 58/21 | 528/223 | ||||||
Age, yr | 3,870 | 10.8 ± 3.54 | 355 | 7.5 ± 5.45 | 382 | 8.6 ± 4.03 | 360 | 8.4 ± 3.74 | 79 |
| 751 | 11.2 ± 3.06 |
HSDS | 3,870 |
| 355 |
| 382 |
| 360 |
| 79 |
| 751 |
|
IGF-I SDS | 3,360 |
| 184 |
| 220 |
| 258 |
| 65 |
| 701 |
|
Bone age, yrs | 3,369 | 9.3 ± 3.41 | 186 | 8.5 ± 4.5 | 256 | 8.0 ± 3.46 | 296 | 7.3 ± 3.68 | 66 | 8.0 ± 3.75 | 667 | 9.6 ± 3.31 |
Baseline GH dose, mg/kg/day | 3,514 | 0.047 (0.0121) | 319 | 0.039 (0.0123) | 357 | 0.051 (0.0098) | 325 | 0.052 (0.0137) | 72 | 0.047 (0.0106) | 644 | 0.050 (0.0127) |
Peak GH, ng/mL | 3,326 | 5.3 ± 2.77 | 202 | 3.1 ± 3.04 | 16 | 18.2 ± 31.54 | 138 | 14.4 ± 13.69 | 32 | 10.8 ± 9.13 | 542 | 17.1 ± 20.09 |
Baseline HSDS (males) | 2918 |
| 220 |
| — | — | 224 |
| 58 |
| 528 |
|
Baseline HSDS (female) | 952 |
| 135 |
| 382 |
| 136 |
| 21 |
| 223 |
|
2.2 ± 0.89
1.9 ± 1.39
2.6 ± 0.9
2.6 ± 0.89
2.7 ± 0.70
2.3 ± 0.75
2.5 ± 1.42
3.2 ± 1.67
1.9 ± 1.22
2.4 ± 1.68
2.8 ± 1.27
2.2 ± 1.45
2.1 ± 0.85
1.9 ± 1.36
2.5 ± 0.83
2.6 ± 0.69
2.2 ± 0.71
2.4 ± 0.97
1.9 ± 1.44
2.6 ± 0.90
2.7 ± 0.97
2.9 ± 0.69
2.4 ± 0.82