Table 1 Previously published case reports of insulinoma in children (1960 - present)
Author | No. of cases | Age –years (Diagnosis/surgery) | Gender | Symptoms | Symptom duration (months) | Imaging/Tumor size(cms) |
|---|---|---|---|---|---|---|
Present case | 1 | 15 | F | Loss of consciousness, vague fatigue, excessive sleepiness, jitteriness, tremors and sweating | 2–3 | MRI/1.5 |
Cameroglu et al. (2016) [9] | 1 | 16 | M | Shakiness, dizziness, disorientation, and unsteadiness | 4 | MRI/9.6 |
Halpin et al. (2016) [10] | 1 | 15 | F | Fatigue, confusion, poor concentration, irritability and “staring off” | 8 | MRI/1.3 |
Mirion et al. (2016) [11] | 1 | 11 | M | Diffuse abdominal pain, cold sweats, confusion, tremor, paresthesias | 5 | MRI/1.0 |
Bhatti et al. (2016) [12] | 12 | 4–16 | M (7) F (5) | NA | 4–108 | NA/0.7–2.0 |
Jung et al. (2015) [13] | 1 | 11 | F | Seizures, palpitations, sweating | 5 | MRI/3.0 |
Padidela et al. (2014) [14] | 9 | 3–15 | M(4) F (5) | Seizures (3) | 1–24 | MRI (7) CT (2)/0.8–2.0 |
Ahmed et al. (2014) [15] | 1 | 10 | M | Episodic tremulousness, diaphoresis, increased hunger, confusion and fainting | 1 | CT/1.7 |
Jyotsna et al. (2014) [16] | 1 | 14 | M | Loss of consciousness, seizures | 24 | MRI/1.8 |
Peranteau et al. (2013) [17] | 8 | 4–26 | M (6) F (2) | NA | 1–84 | MRI (3) CT (2) 18FDOPA PET (3)/0.7–1.8 |
Kao et al. (2013) [18] | 1 | 9 | F | Seizures, early morning behavioral changes | 4 | CT/1.4 |
Horvath et al. (2013) [19] | 1 | 16 | M | Seizures, unusual mental behavior | 6 | CT/1.6 |
Ide et al. (2012) [20] | 1 | 13 | M | Seizures | Unknown | CT/1.9 |
Blasetti et al. (2011) [21] | 1 | 17 | F | Seizures | 9 | CT/1.5 |
Janem et al. (2010) [22] | 1 | 12 | M | Abdominal pain, generalized weakness, sweating and drowsiness | 4 | MRI/NA |
Ozen et al. (2009) [23] | 1 | 16 | M | Seizures, syncope, fatigue, weakness and somnolence | 12 | CT/0.8 |
Strong et al. (2007) [24] | 1 | 13 | M | Seizures | 1 | MRI/1.8 |
Jaladayan et al. (2007) [25] | 1 | 13 | F | Seizures, confusion, unresponsiveness, psychomotor slowing | 6 | MRI/2.5-first tumor – 0.7-0.9- second tumor |
Jaksic et al. (1992) [26] | 2 | 8 | M (1) F (1) | NA | NA | A/1 |
Service et al. (1991) [8] | 13 | NA | NA | NA | NA | NA/NA |
Grosfeld et al. (1990) [27] | 5 | NA | NA | Seizures (1) | NA | CT (3) U/S (1)/NA |
Wolfsdorf et al. (1979) [28] | 1 | 8 | F | Loss of consciousness, lethargy | 0.5 | NA/1.1 |
Mann et al. (1969) [29] | 5 | 3 days- 14 yrs | M (2) F (3) | Seizures, diplopia, fatigue, loss of consciousness, hunger, inability to concentrate, sweating, clumsiness, drowsiness, weakness, incoordination of legs, slurred speech and hallucinations | 0.8–24 | NA/1–1.1 |
Boley et al. (1960) [30] | 2 | 6 months; 10 months | M (1) F (1) | Seizures | 3–6 | NA/NA |