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  1. Research

    Clitoral size in term newborns in Kumasi, Ghana

    Data on normative clitoral sizes in newborns is relatively sparse and racial/ethnic differences have also been reported. This study was performed to establish norms for clitoral size in term Ghanaian female ne...

    Serwah Bonsu Asafo-Agyei, Emmanuel Ameyaw, Jean-Pierre Chanoine, Margaret Zacharin and Samuel Blay Nguah

    International Journal of Pediatric Endocrinology 2017 2017:6

    Published on: 6 June 2017

  2. Research

    Change in BMI after radioactive iodine ablation for graves disease

    We aimed to determine the extent of post-treatment weight gain that occurs in pediatric patients in the first year following radioactive iodine (RAI) therapy for Graves disease (GD) and its relationship to cli...

    Melinda Chen, Matthew Lash, Todd Nebesio and Erica Eugster

    International Journal of Pediatric Endocrinology 2017 2017:5

    Published on: 2 June 2017

  3. Research

    Deferring surgical treatment of ambiguous genitalia into adolescence in girls with 21-hydroxylase deficiency: a feasibility study

    Genital surgery in Disorders of Sex Development (DSD) has been an area of debate over the past 20 years. Emerging scientific evidence in the late 1990s defied the then routine practice to surgically align geni...

    Pierre Bougnères, Claire Bouvattier, Maryse Cartigny and Lina Michala

    International Journal of Pediatric Endocrinology 2017 2017:3

    Published on: 28 January 2017

  4. Research

    Normative penile anthropometry in term newborns in Kumasi, Ghana: a cross-sectional prospective study

    Genital measurements are a useful adjunct in the early detection of various endocrine conditions including hypopituitarism and disorders of sexual differentiation. Standards for genital sizes have been publish...

    Serwah Bonsu Asafo-Agyei, Emmanuel Ameyaw, Jean-Pierre Chanoine and Samuel Blay Nguah

    International Journal of Pediatric Endocrinology 2017 2017:2

    Published on: 26 January 2017

  5. Case report

    Short stature and hypoparathyroidism in a child with Kenny-Caffey syndrome type 2 due to a novel mutation in FAM111A gene

    Hypoparathyroidism in children is a heterogeneous group with diverse genetic etiologies. To aid clinicians in the investigation and management of children with hypoparathyroidism, we describe the phenotype of ...

    Mary B. Abraham, Dong Li, Dave Tang, Susan M. O’Connell, Fiona McKenzie, Ee Mun Lim, Hakon Hakonarson, Michael A. Levine and Catherine S. Choong

    International Journal of Pediatric Endocrinology 2017 2017:1

    Published on: 25 January 2017

  6. Case report

    Rabson Mendenhall Syndrome caused by a novel missense mutation

    Rabson Mendenhall syndrome is a rare endocrine condition characterized by severe insulin resistance and hyperglycemia. It occurs due to mutations in the insulin receptor gene. Few mutations which are associate...

    Krishnapradeep Sinnarajah, M. B. K. C. Dayasiri, N. D. W. Dissanayake, S. T. Kudagammana and A. H. H. M. Jayaweera

    International Journal of Pediatric Endocrinology 2016 2016:21

    Published on: 17 November 2016

  7. Review

    Anti-Müllerian hormone as a marker of steroid and gonadotropin action in the testis of children and adolescents with disorders of the gonadal axis

    In pediatric patients, basal testosterone and gonadotropin levels may be uninformative in the assessment of testicular function. Measurement of serum anti-Müllerian hormone (AMH) has become increasingly widesp...

    Nadia Y. Edelsztein, Romina P. Grinspon, Helena F. Schteingart and Rodolfo A. Rey

    International Journal of Pediatric Endocrinology 2016 2016:20

    Published on: 28 October 2016

  8. Research

    The influence of a long-term growth hormone treatment on lipid and glucose metabolism: a randomized trial in short Japanese children born small for gestational age

    Long-term growth hormone (GH) treatments in short children born small for gestational age (SGA) restore lipid metabolism, but also increase insulin resistance. The aim of this study was to evaluate the influen...

    Reiko Horikawa, Toshiaki Tanaka, Hiromi Nishinaga, Yoshihisa Ogawa and Susumu Yokoya

    International Journal of Pediatric Endocrinology 2016 2016:19

    Published on: 26 October 2016

  9. Research

    Differential effects of hydrocortisone, prednisone, and dexamethasone on hormonal and pharmacokinetic profiles: a pilot study in children with congenital adrenal hyperplasia

    Little is known about the comparative effects of different glucocorticoids on the adrenal and growth hormone (GH) axes in children with congenital adrenal hyperplasia (CAH). We sought to compare the effects of...

    Todd D. Nebesio, Jamie L. Renbarger, Zeina M. Nabhan, Sydney E. Ross, James E. Slaven, Lang Li, Emily C. Walvoord and Erica A. Eugster

    International Journal of Pediatric Endocrinology 2016 2016:17

    Published on: 26 September 2016

  10. Research

    Body mass index in girls with idiopathic central precocious puberty during and after treatment with GnRH analogues

    In girls with Idiopathic Central Precocious Puberty (ICPP) concern has been raised by the potential impact of GnRH-analogues (GnRHa) treatment on body weight. We evaluated the effect of GnRHa on Body Mass Inde...

    A. J. Arcari, M. G. Gryngarten, A. V. Freire, M. G. Ballerini, M. G. Ropelato, I. Bergadá and M. E. Escobar

    International Journal of Pediatric Endocrinology 2016 2016:15

    Published on: 5 August 2016

  11. Case report

    Vague neuroglycopenic complaints camouflage diagnosis of adolescent insulinoma: a case report

    Insulinoma is a rare diagnosis in the general population with estimates of 1 in 250,000 people per year. Reports of these pancreatic islet cell tumors are even more unusual in children and adolescents. Chronic...

    Kelsee Halpin, Ryan McDonough, Patria Alba, Jared Halpin, Vivekanand Singh and Yun Yan

    International Journal of Pediatric Endocrinology 2016 2016:14

    Published on: 29 July 2016

  12. Case report

    46,XY disorder of sex development due to 17-beta hydroxysteroid dehydrogenase type 3 deficiency: a plea for timely genetic testing

    17β-hydroxysteroid dehydrogenase type 3 (17βHSD3) deficiency is a rare cause of disorder of sex development (DSD) due to impaired conversion of androstenedione to testosterone. Traditionally, the diagnosis was...

    Chelsey Grimbly, Oana Caluseriu, Peter Metcalfe, Mary M. Jetha and Elizabeth T. Rosolowsky

    International Journal of Pediatric Endocrinology 2016 2016:12

    Published on: 15 June 2016

  13. Case report

    Positive fertility outcomes in a female with classic congenital adrenal hyperplasia following bilateral adrenalectomy

    Classic congenital adrenal hyperplasia (CAH) requires lifetime steroid replacement and supraphysiologic glucocorticoid dose is often required for adequate adrenal androgen suppression. Patients often suffer fr...

    Urania Dagalakis, Ashwini Mallappa, Meredith Elman, Martha Quezado and Deborah P. Merke

    International Journal of Pediatric Endocrinology 2016 2016:10

    Published on: 20 May 2016

  14. Research

    Influences of gender on cardiovascular disease risk factors in adolescents with and without type 1 diabetes

    Women with type 1 diabetes (T1D) have a four-fold increased risk for cardiovascular disease (CVD) compared to non-diabetic (non-DM) women, as opposed to double the risk in T1D men compared to non-DM men. It is...

    Talia L. Brown, David M. Maahs, Franziska K. Bishop, Janet K. Snell-Bergeon and R. Paul Wadwa

    International Journal of Pediatric Endocrinology 2016 2016:8

    Published on: 19 April 2016

  15. Research

    An audit of the management of childhood-onset growth hormone deficiency during young adulthood in Scotland

    Adolescents with childhood onset growth hormone deficiency (CO-GHD) require re-evaluation of their growth hormone (GH) axis on attainment of final height to determine eligibility for adult GH therapy (rhGH).

    M. Ahmid, V. Fisher, A. J. Graveling, S. McGeoch, E. McNeil, J. Roach, J. S. Bevan, L. Bath, M. Donaldson, G. Leese, A. Mason, C. G. Perry, N. N. Zammitt, S. F. Ahmed and M. G. Shaikh

    International Journal of Pediatric Endocrinology 2016 2016:6

    Published on: 16 March 2016

  16. Research

    Efficacy of growth hormone replacement on anthropometric outcomes, obesity, and lipids in children with optic nerve hypoplasia and growth hormone deficiency

    Hypopituitarism and obesity are causes of major lifelong morbidity in patients with optic nerve hypoplasia (ONH). Growth hormone deficiency (GHD) affects the majority of children with ONH, though the degree of...

    Carly Stewart, Pamela Garcia-Filion, Cassandra Fink, Anna Ryabets-Lienhard, Mitchell E. Geffner and Mark Borchert

    International Journal of Pediatric Endocrinology 2016 2016:5

    Published on: 2 March 2016

  17. Research

    Increasing incidence of premature thelarche in the Central Region of Denmark - Challenges in differentiating girls less than 7 years of age with premature thelarche from girls with precocious puberty in real-life practice

    Premature thelarche (PT) seems to be increasing and it is difficult to differentiate its early stages from precocious puberty (PP). Clinical and biochemical parameters are warranted to differentiate the two di...

    Mia Elbek Sømod, Esben Thyssen Vestergaard, Kurt Kristensen and Niels Holtum Birkebæk

    International Journal of Pediatric Endocrinology 2016 2016:4

    Published on: 22 February 2016

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International Journal of Pediatric Endocrinology is affiliated with the Asia Pacific Paediatric Endocrine Society (APPES)

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