Baseline | 1 yr | 2 yrs | 3 yrs | ||||||
---|---|---|---|---|---|---|---|---|---|
Treated | Untreated | Treated | Untreated | Treated | Untreated | Treated | Untreated | After Tx | |
CA (yr) | 7.3 ± 1.5 | 7.7 ± 0.7 | 8.3 ± 1.5 | 8.7 ± 0.9 | 9.2 ± 1.5 | 9.6 ± 0.7 | 10.1 ± 1.5 | 10.7 ± 1.2 | 11.04 ± 0.4 |
Weight (z-score) | 1.4 ± 0.7 | 1.2 ± 0.8 | 1.4 ± 0.6 | 1.3 ± 0.8 | 1.3 ± 0.9 | 1.2 ± 0.7 | 1.6 ± 0.6* | 0.9 ± 0.5 | 0.8 ± 0.9 |
BMI (z-score) | 1.2 ± 0.9 | 1 ± 0.8 | 1.2 ± 0.7 | 1.1 ± 0.8 | 1.1 ± 1 | 1 ± 0.7 | 1.3 ± 0.8 | 0.7 ± 0.5 | 0.7 ± 0.9 |
Ob/over (%) | 79.3 | 50 | 65.4 | 50 | 65.4 | 50 | 81.8 | 40 | 40 |
Obesity (%) | 24.1 | 25 | 26.9 | 25 | 23.1 | 25 | 45.5 | 0 | 20 |
Overweight (%) | 55.2 | 25 | 38.5 | 25 | 42.3 | 25 | 36.4 | 40 | 20 |
Glycemia (mg/dl) | 73.1 ± 9.1 | 74 ± 7.6 | 79.6 ± 8.9 | 88.6 ± 6.5 | 76 ± 10.1 | 84.3 ± 11.7 | 84.4 ± 5.3 | 80 ± 2.6 | 81 ± 18.4 |
Total-C (mg/dl) | 156 ± 31.5 | 167.6 ± 35.7 | 172.1 ± 34.8 | 146.5 ± 42.3 | 152.8 ± 38.6 | 177.3 ± 23.9 | 159.2 ± 26.5 | 171.7 ± 39.1 | 167.3 ± 19.4 |
LDL-C (mg/dl) | 96.6 ± 38.1 | 99.5 ± 16.3 | 108.1 ± 19.1 | 71.3 ± 24.1 | 92.9 ± 30.5 | 112.5 ± 7.8 | 100.2 ± 22.8 | 128.8 ± 13.9 | 122.5 ± 2.1 |
HDL-C (mg/dl) | 43.8 ± 9 | 52 ± 7.1 | 35 ± 10.1 | 37.3 ± 9 | 48.5 ± 12.8 | 37 ± 4.2 | 43.8 ± 14 | 45.5 ± 2.1 | 44.5 ± 14.9 |
TRG (mg/dl) | 83.3 ± 36.2 | 115.8 ± 78.5 | 80.9 ± 30.7 | 90.8 ± 33.7 | 79.9 ± 46.5 | 117 ± 66.8 | 83.3 ± 52.7 | 98.5 ± 37.5 | 64 ± 31.1 |
TRG/HDL-C ratio | 2.1 ± 0.8 | 3 ± 1.5 | 2.5 ± 1 | 2.4 ± 0.5 | 1.7 ± 1.2 | 2.9 ± 2.2 | 1.9 ± 1.3 | 2.2 ± 0.9 | 2 ± 0.8 |