From: Endocrine manifestations and management of Prader-Willi syndrome
Phase | Description | Median Age of Onset and Completion |
---|---|---|
0 | Decreased fetal movement and lower birth weight | In utero |
1a | Hypotonia with difficulty feeding | 0-9Â months |
1b | No difficulty feeding and growing appropriately | 9-25Â months |
2a | Weight increasing without increase in appetite or excessive calories | 2.1-4.5Â years |
2b | Weight increasing with an increase in appetite | 4.5-8Â years |
3 | Hyperphagic, rarely feels full | 8Â years - adulthood |
4 | Appetite no longer insatiable | adulthood |