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Table 3 Comparison of clinical characteristics of patients with premature adrenarche based on race

From: Low prevalence of organic pathology in a predominantly black population with premature adrenarche: need to stratify definitions and screening protocols

 

non-Hispanic white (n = 55)

Black (n = 205)

Other (n = 6)

p-value

Female % (n)

80 (44)

75.6 (155)

83.3 (5)

NS

Age at initial evaluation (years)

6.67 +/−  1.83

6.30+/−  2.02

7.94 +/−  1.00

NS

Age at initial symptoms/ signs (years)

5.42 +/− 1.89

4.44 +/−  2.01

6.48 +/−  2.15

0.004*

Weight z-score

1.32 +/− 1.07

1.25 +/−  1.39

0.84+/−  1.56

NS

BMI z-score

1.28 +/− 0.92

1.24 +/−1.29

1.33 +/−  0.83

NS

Systolic BP

106 +/− 7.44

103+/−  7.85

101.29 +/−  8.83

0.008*

Diastolic BP

65.5 +/− 6.47

64.4 +/−6.77

67.0+/−  6.03

NS

Hypertension % (n)

16.4 (9)

11.2 (23)

16.7 (1)

NS

Tanner stage (pubic hair)

2.09 +/− 0.53

2.33 +/−  0.59

1.83 +/−  0.41

0.006*

Testosterone (ng/dL)

11.2 +/− 17.0

6.78 +/− 5.32

6.97 +/−  1.50

NS

17-OH progesterone (ng/dL)

34.0 +/− 35.6

26.4 +/− 24.1

35.0 +/− 9.64

NS

DHEA-sulfate (ug/dL)

97.7 +/− 78.7

76.0+/−  48.6

108 +/−  102

NS

Androstenedione (ng/dL)

18.0 +/− 9.46

19.5+/− 8.05

20.5 +/−9.19

NS

  1. Values listed are means and standard deviation
  2. NS not significant
  3. *Statistically significant difference at the P < 0.05