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Table 2 Adrenal and testicular function after cortrosyn and hCG stimulation obtained at 8 months

From: Undervirilized male infant with in utero exposure to maternal use of high dose antifungal therapy

CORTROSYN STIMULATION TEST (250 mcg) Reference value Baseline Stimulated (1 h)
ACTH (pg/ml) 6–48 11  
Cortisol (mcg/dl) 2.8–23 19 29
Aldosterone (ng/dl) 5–90 38  
Renin (ng/ml/hr) 2–37 7.8  
17-Hydroxypregnenolone (ng/dl) 42–540 528 1150
17-Hydroxyprogesterone (ng/dl) < 91 57 182
Androstenedione (ng/dl) < 10–37 < 10 < 10
DHEA (ng/dl) < 136 78 114
Testosterone (ng/dl) < 2.5–10 3.6 3.8
Dihydrotestosterone (ng/dl) < 3 1.4  
Corticosterone (ng/dl) 80–1500 871  
Deoxycorticosterone (ng/dl) 7–49 15 43
11-Deoxycortisol (ng/dl) < 10–156 54 107
Estrone (pg/ml) < 15 < 2.5 6
Progesterone (ng/dl) < 10–15 < 10 52
hCG STIMULATION TEST (15,000 IU over 3 days)   Baseline Day 4
LH (mIU/ml) 0.02–7 0.228  
FSH (mIU/ml) 0.16–4.1 1.3  
Testosterone (ng/dl) < 2.5–10 3.6 587
Dihydrotestosterone (ng/dl) < 3 1.4 111
Androstenedione (ng/dl) < 10–37 < 10 15
Estrone (pg/ml) < 15 < 2.5 3.8
Estradiol (pg/ml) < 15 < 1 1.5