Fig. 4

Three dimensional model of DHH. a SWISS-MODEL generated 3D model of DHH showing residue Leu162, the position of a previously published mutation [12] and b Arg164, the position of our novel mutation. c Close-up of the mutation L162P and d R164P with the side chains of both the wild-type and mutant residue shown and coloured green and red, respectively. On panels a and b, black arrows point to position of mutations