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Fig. 3 | International Journal of Pediatric Endocrinology

Fig. 3

From: A novel, homozygous mutation in desert hedgehog (DHH) in a 46, XY patient with dysgenetic testes presenting with primary amenorrhoea: a case report

Fig. 3

Histopathology. a Right gonad excision biopsy, H&E stain, demonstrating seminiferous tubules lined by Sertoli cells without spermatogenesis. There is intervening fibrosis with no definite Leydig cells. b Left gonad excision biopsy, H&E stain, demonstrating seminiferous tubules lined by Sertoli cells without spermatogenesis. There is intervening fibrosis with occasional, unusually large clusters of Leydig cells. c Left gonad excision, inhibin stain, demonstrating Sertoli and Leydig cell appearance. d Normal testis of 15-year-old, showing seminiferous tubules with spermatogenesis

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