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Table 3 Correlation coefficients of measurements of body composition, IGF-1, appetite regulating peptides and measurements of glucose homeostasis within the PWS patients (total group)

From: Body composition, adipokines, bone mineral density and bone remodeling markers in relation to IGF-1 levels in adults with Prader-Willi syndrome

  BMI FM LBM IGF-1 Glucose HbA1c Insulin HOMA Leptin Ghrelin Resistin Adiponectin Hs-CRP
BMI (kg/m2) 1.00 0.96** 0.75** − 0.18 0.19 0.16 0.44 0.55* 0.83** −0.44 0.58* −0.31 0.77**
FM (g, DXA) 0.96** 1.00 0.69** −0.14 0.19 0.18 0.36 0.46 0.78** −0.33 0.53* −0.30 0.88**
LBM (g, DXA) 0.75** 0.69** 1.00 0.02 0.02 0.32 0.46 0.51 0.54* −0.46 0.69** −0.44 0.66**
IGF-1 (nmol/L) −0.18 −0.14 0.02 1.00 −0.03 −0.18 0.26 0.04 −0.04 −0.11 0.01 −0.39 − 0.27
Glucose (mmol/L) 0.19 0.19 0.02 −0.03 1.00 0.14 0.67** 0.65* 0.51* −0.34 0.20 −0.45 0.39
HbA1c (%) 0.16 0.18 0.32 −0.18 0.14 1.00 0.02 0.09 0.14 0.10 0.35 −0.58* 0.41
Insulin (pmol/L) 0.44 0.36 0.46 0.26 0.67** 0.02 1.00 0.99** 0.69** −0.48 0.39 −0.46 0.33
HOMA (index) 0.55* 0.46 0.51 0.04 0.65* 0.09 0.99** 1.00 0.67** −0.58* 0.54* −0.34 0.41
Leptin (μg/L) 0.83** 0.78** 0.54* −0.04 0.51* 0.14 0.69** 0.67** 1.00 −0.41 0.37 −0.39 0.66**
Ghrelin (ng/L) −0.44 −0.33 − 0.46 −0.11 − 0.34 0.10 − 0.48 −0.58* − 0.41 1.00 − 0.31 0.29 − 0.24
Resistin (ng/ml) 0.58* 0.53* 0.69** 0.01 0.20 0.35 0.39 0.54* 0.37 −0.31 1.00 −0.56* 0.51*
Adiponectin (mg/L) −0.31 −0.30 − 0.44 −0.39 − 0.45 −0.58* − 0.46 −0.34 − 0.39 0.29 − 0.56* 1.00 − 0.47
Hs-CRP (mg/L) 0.77** 0.88** 0.66** −0.27 0.39 0.41 0.33 0.41 0.66** −0.24 0.51* −0.47 1.00
  1. * Significant correlation, p < 0.05; ** p < 0.01