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Table 2 IGF-1 levels, markers of metabolic status, bone remodeling markers and appetite regulating factors in PWS patients (panel A) and IGF-1 levels in healthy controls (panel B)

From: Body composition, adipokines, bone mineral density and bone remodeling markers in relation to IGF-1 levels in adults with Prader-Willi syndrome

Panel A PWS
  Total group   Men   Women  
  (N = 15) IQR (N = 4) IQR (N = 11) IQR
IGF-1, nmol/L 14.6 7.7 16.0 11.9 14.6 7.7
IGF-1, SDS −1.94 1.24 −1.55 1.24 −1.96 1.00
IGFBP-3, mg/L 4.30 1.38 4.73 2.87 4.02 1.89
Calcium, mmol/L 2.42 0.17 2.43 0.30 2.42 0.09
Albumin, g/L 43.0 5.0 42.5 12.0 43.0 4.0
Creatinine, μmol/L 69.0 10.0 71.0 28.0 69.0 10.0
Alkaline phosphatase, U/L 103.0 54.0 98.0 57.0 106.0 61.0
Phosphate, mmol/L 1.12 0.31 0.91 0.47 1.16 0.26
25(OH)D, nmol/L 61.0 34.0 83.5 66.0 54.0 31.0
Osteocalcin, nmol/L 0.90 2.49 0.77 2.28 1.24 2.49
Total cholesterol, mmol/L 4.8 1.8 4.9 2.6 4.8 1.8
HDL, mmol/L 1.3 0.5 1.2 0.7 1.3 0.4
LDL, mmol/L 2.9 1.2 2.1 NA 3.2 1.0
Triglycerides, mmol/L 0.80 0.30 1.75 2.60 0.80 0.30
Glucose, mmol/L 4.2 1.0 4.2 0.2 4.0 1.3
HbA1c, % 5.4 0.4 5.6 3.1 5.4 0.4
Insulin, pmol/L 30.6 36.8 37.2 179.1 29.1 38.5
HOMA index 0.58 0.62 0.66 3.04 0.55 0.64
Leptin, μg/L 21.5 33.2 20.1 38.7 24.9 33.2
Ghrelin, ng/L 2476 2080 2118 2201 2612 2092
Resistin, ng/ml 4.4 3.6 4.3 5.7 4.4 3.6
Adiponectin, mg/L 13.9 6.7 13.2 9.1 13.9 6.4
Hs-CRP, mg/L 4.04 10.39 3.48 8.01 7.54 19.68
Urine Calcium, mmol/24 h 0.20 0.5 0.55 1.1 0.20 0.2
Urine Creatitine, mmol/24 h 1.74 1.47 3.27 2.86 1.70 0.69
Urine Hydroxyprolin, mmol/24 h 0.046 0.028 0.055 0.087 0.046 0.027
Urine Hydroxyprolin/Creatinin ratio 25.2 21.2 23.2 40.9 25.2 20.4
Panel B Controls
  Total group   Men   Women  
  (N = 14) IQR (N = 7) IQR (N = 7) IQR
IGF-1, nmol/L 21.8 11.6 21.4 14.2 22.1 10.5
IGF-1, SDS −0.79 1.06 −1.00 1.07 − 0.76 1.72
  1. All data are presented as median with interquartile range (IQR)