Skip to main content

Table 1 Body composition characteristics and measurements of bone mineral density in PWS patients and control group

From: Body composition, adipokines, bone mineral density and bone remodeling markers in relation to IGF-1 levels in adults with Prader-Willi syndrome

 

PWS

Controls

Total group

 

Men

 

Women

 

Total group

 

Men

 

Women

 

(N = 15)

IQR

(N = 4)

IQR

(N = 11)

IQR

(N = 14)

IQR

(N = 7)

IQR

(N = 7)

IQR

Age, years

22.0

12.9

26.6

18.3

20.9

12.9

28.5

18.0

28.4

17.4

28.7

20.1

Sex

 Female, %

73.3

     

50.0

     

 Male, %

26.7

     

50.0

     

Genetic subtype

 Deletion, %

93.3

           

 UPD, %

6.7

           

Height, m

1.58**

0.08

1.60

0.09

1.57

0.10

1.77

0.17

1.86##

0.066

1.69

0.048

Weight, kg

69.5

33.6

67.9

32.9

70.3

37.1

73.1

15.9

79.1#

15.9

65.2

14.1

BMI, kg/m2

27.5*

16.7

26.1

13.2

32.1

20.3

22.4

4.6

22.7

5.1

22.0

5.8

Waist, cm

94.8*

27.5

94.3

17.1

94.8

43.8

80.2

19.3

84.5

11.4

71.2

24.2

Hip, cm

107

33.3

102.5

21.1

120.2

34.2

98.9

8.0

102.1

5.4

97.8

15.3

WHR

0.87*

0.13

0.93

0.12

0.87

0.10

0.82

0.14

0.84#

0.07

0.73

0.10

FM, kg (BIA)

28.5**

23.5

25.4

21.6

30.1

23.5

14.2

9.9

13.8

2.9

14.5

10.0

FFM, kg (BIA)

44.2**

16.2

44.2

16.1

44.2

16.2

56.2

18.0

66.2#

13.6

48.5

5.7

FM, % (BIA)

42.4**

12.4

37.5

12.3

42.4

11.1

20.6

12.3

16.7

4.8

25.1

12.1

FFM, % (BIA)

57.6**

12.4

62.5

12.4

57.6

11.1

79.4

12.3

83.3

4.8

74.9

12.1

BMC, % (BIA)

30.0**

11.4

32.5

8.1

29.7

12.2

42.8

9.7

44.5

7.3

40.3

22.1

BMC Lumbar spine, g (DXA)

41.0

13.8

41.7

17.0

41.0

11.4

 

BMD Lumbar spine, g/cm2 (DXA)

0.91

0.17

0.80

0.28

0.93

0.20

T-score Lumbar spine, SDS (DXA)

−1.4

2.0

−2.6#

2.5

−0.9

1.5

Z-score Lumbar spine, SDS (DXA)

−1.7

1.4

−2.6

2.4

− 1.0

1.7

BMC Total hip, g (DXA)

23.0

5.1

22.9

3.5

23.0

8.4

BMD Total hip, g/cm2 (DXA)

0.76

0.10

0.74

0.13

0.76

0.15

T-score Total hip, SDS (DXA)

−1.6

0.9

−2.0#

0.9

−1.2

1.5

Z-score Total hip, SDS (DXA)

−1.5

1.1

−2.0

0.8

−1.4

1.3

Total BMC, g (DXA)

1763

386

1684

368

1763

423

Total BMD, g/cm2 (DXA)

0.99

0.13

0.95

0.14

0.99

0.14

FM, kg (DXA)

33.5

19.4

28.5

17.1

39.5

26.5

LBM, kg (DXA)

40.5

13.0

41.3

13.1

40.5

15.3

FM, % (DXA)

45.1

11.4

40.4

9.3

47.8

12.5

  1. BMI body mass index, WHR waist-to-hip ratio, FM fat mass, FFM fat free mass, BMC bone mineral content, BMD bone mineral density, LBM lean body mass
  2. All data are presented as median with interquartile range (IQR)
  3. * Significant difference when compared to control group, p < 0.05; ** p < 0.01
  4. # Significant difference when compared to other sex within group, p < 0.05; ## p < 0.01