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Table 1 Potential factors associated with weight gain in patients following RAI treatment of GD

From: Change in BMI after radioactive iodine ablation for graves disease

Variable – Mean ± SD Median (range) Whole population (n = 157) Sub-analysis (n = 81)
Age 12.68 ± 3.00 y 12.79 ± 3.02 y
12.86 (5.34-17.89) y 12.77 (5.34-17.83) y
∆BMI SDS p-value ∆BMI SDS p-value
Gender Female (%)
0.71 ± 0.66 (79.6)
Male (%)
0.71 ± 0.92 (20.4)
0.99 Female (%)
0.69 ± 0.65 (85.2)
Male (%)
0.35 ± 0.47 (14.8)
0.09
0.61 (−0.4-2.97) 0.41 (−0.55-3.85) 0.69 (−0.4-2.68) 0.24 (−0.55-1.24)
Yes (%) No (%) Yes (%) No (%)
ATD use 0.64 ± 0.68 (21) 0.73 ± 0.73 (79) 0.55 0.67 ± 0.77 (18.5) 0.63 ± 0.60 (81.5) 0.81
0.46 (−0.37-2.68) 0.54 (−0.55-3.85)   0.55 (−0.25-2.68) 0.66 (−0.55-2.04)  
Down syndrome 0.85 ± 0.86 (6.4) 0.70 ± 0.71 (93.6) 0.53 1.04 ± 0.90 (7.4) 0.61 ± 0.60 (92.6) 0.10
0.88 (0.0-2.68) 0.53 (−0.55-3.85)   0.88 (0.17-2.68) 0.59 (−0.55-2.04)  
ADHD treatment 0.97 ± 1.08 (7.6) 0.69 ± 0.68 (92.4) 0.40 0.98 ± 0.79 (4.9) 0.62 ± 0.62 (95.1) 0.26
0.44 (0.08-3.85) 0.55 (−0.55-2.97)   0.97 (0.08-1.92) 0.59 (−0.55-2.68)  
History of weight loss 0.92 ± 0.84 (38.2) 0.56 ± 0.57 (49) 0.005* 0.77 ± 0.62 (39.5) 0.55 ± 0.56 (50.6) 0.12
0.74 (−0.55-3.85) 0.45 (−0.4-2.47)   0.74 (−0.55-2.00) 0.57 (−0.4-2.04)  
Pubertal 0.67 ± 0.63 (56.1) 0.91 ± 0.90 (29.9) 0.10 0.57 ± 0.58 (56.8) 0.90 ± 0.71 (29.6) 0.04*
0.49 (−0.4-2.71) 0.75 (−0.37-3.85)   0.50 (−0.4-2.04) 0.82 (−0.35-2.68)  
  1. Significant findings (p < 0.05) are marked with an asterisk (*). Mean ± SD are on line 1 and median, range on line 2 for all variables. Not all percentages add to 100% due to missing patient information. BMI = body mass index; ATD = anti-thyroid drug; ADHD = attention deficit-hyperactivity disorder
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