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Table 1 Potential factors associated with weight gain in patients following RAI treatment of GD

From: Change in BMI after radioactive iodine ablation for graves disease

Variable – Mean ± SD Median (range)

Whole population (n = 157)

Sub-analysis (n = 81)

Age

12.68 ± 3.00 y

12.79 ± 3.02 y

12.86 (5.34-17.89) y

12.77 (5.34-17.83) y

∆BMI SDS

p-value

∆BMI SDS

p-value

Gender

Female (%)

0.71 ± 0.66 (79.6)

Male (%)

0.71 ± 0.92 (20.4)

0.99

Female (%)

0.69 ± 0.65 (85.2)

Male (%)

0.35 ± 0.47 (14.8)

0.09

0.61 (−0.4-2.97)

0.41 (−0.55-3.85)

0.69 (−0.4-2.68)

0.24 (−0.55-1.24)

Yes (%)

No (%)

Yes (%)

No (%)

ATD use

0.64 ± 0.68 (21)

0.73 ± 0.73 (79)

0.55

0.67 ± 0.77 (18.5)

0.63 ± 0.60 (81.5)

0.81

0.46 (−0.37-2.68)

0.54 (−0.55-3.85)

 

0.55 (−0.25-2.68)

0.66 (−0.55-2.04)

 

Down syndrome

0.85 ± 0.86 (6.4)

0.70 ± 0.71 (93.6)

0.53

1.04 ± 0.90 (7.4)

0.61 ± 0.60 (92.6)

0.10

0.88 (0.0-2.68)

0.53 (−0.55-3.85)

 

0.88 (0.17-2.68)

0.59 (−0.55-2.04)

 

ADHD treatment

0.97 ± 1.08 (7.6)

0.69 ± 0.68 (92.4)

0.40

0.98 ± 0.79 (4.9)

0.62 ± 0.62 (95.1)

0.26

0.44 (0.08-3.85)

0.55 (−0.55-2.97)

 

0.97 (0.08-1.92)

0.59 (−0.55-2.68)

 

History of weight loss

0.92 ± 0.84 (38.2)

0.56 ± 0.57 (49)

0.005*

0.77 ± 0.62 (39.5)

0.55 ± 0.56 (50.6)

0.12

0.74 (−0.55-3.85)

0.45 (−0.4-2.47)

 

0.74 (−0.55-2.00)

0.57 (−0.4-2.04)

 

Pubertal

0.67 ± 0.63 (56.1)

0.91 ± 0.90 (29.9)

0.10

0.57 ± 0.58 (56.8)

0.90 ± 0.71 (29.6)

0.04*

0.49 (−0.4-2.71)

0.75 (−0.37-3.85)

 

0.50 (−0.4-2.04)

0.82 (−0.35-2.68)

 
  1. Significant findings (p < 0.05) are marked with an asterisk (*). Mean ± SD are on line 1 and median, range on line 2 for all variables. Not all percentages add to 100% due to missing patient information. BMI = body mass index; ATD = anti-thyroid drug; ADHD = attention deficit-hyperactivity disorder