Fig. 2

AMH as a marker of FSH action in the prepubertal testis. FSH provokes Sertoli cell proliferation and increases AMH transcription in each Sertoli cell through the classical FSH receptor (FSH-R) transduction pathway involving Gsα protein, adenylyl cyclase (AC) and stimulation of protein kinase A (PKA) activity, leading to an increased AMH promoter activity induced by transcription factors SOX9, SF1, GATA4, NFκB and AP2