Skip to main content
Fig. 1 | International Journal of Pediatric Endocrinology

Fig. 1

From: Anti-Müllerian hormone as a marker of steroid and gonadotropin action in the testis of children and adolescents with disorders of the gonadal axis

Fig. 1

Developmental physiology of the testis in postnatal life. a: Testicular volume increases slightly during infancy and childhood (from birth to the age of 8–10 yr), as measured by ultrasonography, mainly due to the increase of the Sertoli cell population. After pubertal onset, clinically defined by a testicular volume of 4 ml as measured by comparison with the orchidometer, testicular volume increases drastically due to the onset of pubertal spermatogenesis, which requires androgen-dependent Sertoli cell maturation. b: Schematic serum levels of gonadotropins (FSH and LH), testosterone (T), inhibin B (Inh B) and AMH from birth through adulthood (left axis) and percentage of Sertoli cells expressing the androgen receptor (AR, right axis). Reprinted, with permission, from Rey et al. [85], copyright 2009 Wiley-Liss, Inc.

Back to article page