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Fig. 4 | International Journal of Pediatric Endocrinology

Fig. 4

From: Differential effects of hydrocortisone, prednisone, and dexamethasone on hormonal and pharmacokinetic profiles: a pilot study in children with congenital adrenal hyperplasia

Fig. 4

In a, when comparing the ABCB1 *1 dominant haplotype with the ABCB1 recessive haplotypes *1/*2 and *2, the subjects homozygous for the *1 haplotype had less suppression of 17-OHP on DEX compared to the others. In b, those expressing the dominant genotype had greater suppression of androstenedione on PDN than the recessive genotype

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