|
Age (years)
|
−7.6
|
0.02*
| |
NS
|
|
Weight (kg)
|
−2.5
|
0.002 **
|
−1.4
|
0.06#
|
|
Weight inverse (1/kg)
|
1153.9
|
0.004 **
| |
NS
|
|
Height (m)
|
−174.1
|
0.001 **
|
−85.9
|
0.08#
|
|
BMI (kg/m2)
|
−6.5
|
0.04*
| |
NS
|
|
BSA (m2)
|
−123.8
|
0.001 **
|
−67.4
|
0.05#
|
|
BMI z-score
|
−14.6
|
NS
| |
NS
|
|
Height z-score
|
−41.7
|
<0.0005**
|
−33.4
|
<0.005**
|
|
Sex (vs female)
|
−42.8
|
0.18#
|
−19.1
|
NS
|
|
Race
| |
NS
| |
NS
|
|
Ethnicity (Hispanic/Latino vs Non-Hispanic/Latino)
| |
NS
|
−94.3
|
0.09#
|
|
Pubertal status (vs Tanner I)
| |
0.21
| |
0.09#
|
|
Tanner II-IV
| |
NS
| |
NS
|
|
Tanner V
|
−115.2
|
0.14#
|
−154.7
|
0.03*
|
|
Pubic hair development (yes vs no)
| |
NS
| |
NS
|
|
Indication for testing (vs GH sufficient short stature)
| |
<0.0005**
| |
<0.0005**
|
|
GHD
| |
NS
| |
NS
|
|
Concern for multi-pituitary abnormalities
|
−65
|
0.11#
|
−55.1
|
0.16
|
|
Neoplasm with risk to pituitary
| |
NS
| |
NS
|
|
Exogenous glucocorticoid exposure
|
−312.7
|
<0.0005**
|
−239.0
|
<0.0005**
|
|
Known multi-pituitary abnormalities
|
−133.7
|
0.02*
|
−105.3
|
0.05
|
|
Time of testing (PM vs AM)
|
−40.1
|
0.17#
|
−62.2
|
0.02*
|
|
Baseline cortisol (nmol/L)
|
0.72
|
<0.0005**
|
−0.35
|
<0.0005**
|
|
Baseline ACTH (pmol/L)
|
10.6
|
0.01*
|
−5.9
|
0.11#
|
|
Delta ACTH (pmol/L)
|
3.4
|
<0.0005**
|
4.0
|
<0.0005**
|
|
Peak ACTH (pmol/L)
|
3.6
|
<0.0005**
|
3.6
|
<0.0005**
|
