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Table 1 Clinical characteristics and immunohistochemical staining results

From: Association of immunohistochemical markers with premalignancy in Gonadal Dysgenesis

Patient Age Diagnosis Sex assignment (M/F) Karyotype Gonadal location EMS out of 12 Malignancy Gonadal tissue type OCT 3/4 PLAP Β-Catenin AFP CD117
1 6 y XY PGD F 45,X[16]/46,X + mar[4], SRY positive Abdomen 1 No Streak - - ++C - +C
2 11 y XY PGD F 45,X/46,XY Abdomen 1 No Streak - - ++C - +C
3 12 y XY PGD F 45,X/46,XY Abdomen 1 No Streak - - ++C - -
4 16 y XY PGD F 45,X[11]/46, X, idic (Y) (q11.21) Abdomen 1 No Streak - - ++N - -
5 7 m XY PGD M 45, X/46, XY L- abdomen 8.5 No Streak - - ++C - -
R- scrotum
6 7 m XY PGD M 45, X/46, XY L-Scrotum 11.5 No Streak - - ++C - -
R-abdomen
7 4 m XX PGD M 46, XX Inguinal 3 No O/T +C, T & O - ++C, T & O - +C, T
++C, O
8 6 m XX PGD M 46, XX Inguinal 4 No O/T +C, T & O - ++C, T & O - +C, T
++C, O
9 2 y XX PGD M 46, XX Inguinal 5 No O/T +C, T & O - -T - -T
++C, O ++C, O
10 5 m XY PGD M 46, XX/46, XXY L-scrotum 6 No O/T ++N, T ++C, T ++C, T & O - ++C, T & O
R- abdomen
+C, O -O
11 8 m XY PGD M 46, XY with mosaicism for 45, X/46, XY in 40 % of cells L- abdomen R- scrotum 6.5 No O/T - - ++C ++C +C
12 9 y XY PGD M 46, XY/47, XXY/45,X Abdomen 8 No O/T - - ++C - -T
+C, O
13 14 m XX PGD M 46, XX L- inguinal 8.5 No O/T ++N ++C ++C - ++C
R- scrotum
14a 12 m XY PGD M 45, X/46, XY R abdomen 8 No O/T ++N ++C ++C - ++C
14b 33 m XY PGD M 45, X/46, XY L-scrotal 8 No Dysgenetic Testis +N - ++C - +C
15 15 y XY PGD F 46, XY and gain of chrom 16p11.2 Inguinal 2 No Dysgenetic Testis - - +C - -
16 2 m XY PGD F 45, X/46, XY Abdomen 4 No Dysgenetic Testis ++N ++C ++C - ++C
17 22 m XY PGD F 45, X/46, XY Inguinal 5 No Dysgenetic Testis ++N ++C ++C - +C
18 4 y XY PGD F 46, XY with gain of chrom 2q14.1 Inguinal 5 No Dysgenetic Testis - - ++C - -
Patient Age Diagnosis Sex assignment (M/F) Karyotype Gonadal location EMS out of 12 Malignancy Gonadal tissue type OCT 3/4 PLAP Β-Catenin AFP CD117
19 16 y XY PGD F 46, XY Inguinal 5 No Dysgenetic Testis +C - ++C - +C
20 11 m XY PGD M 46, XY Inguinal 6 No Dysgenetic Testis - - - - -
21 6 m XY PGD M 46, XY L-scrotum 9 No Dysgenetic Testis ++N ++C ++C - ++C
R- abdomen
22 20 m XY PGD M 45, X/46, XY Inguinal 9 No Dysgenetic Testis - - ++C - -
23 7 m XY PGD F 46, XY, t(11;16)(q22.1;q12.2) Abdomen 1 GB-like GB-like arising from immature testicular tissue ++N ++C ++C - ++C
24 11 m XY PGD M 46, XY L- abdomen 9.5 L gonad- GB GB arising from streak-like ovarian tissue ++N ++C ++C - ++C
R- scrotum
25 17 y XY CGD F 46, XY Abdomen 1 GB with DG DG and GB arising from steak gonad with Ovarian stroma ++N ++C ++C - ++C
26 18 y XY CGD F 46, XY Abdomen 1 R ovary- GB & DG GB and DG arising from streak gonad with Ovarian stroma ++N ++C ++C - ++C
L ovary- GB
  1. PGD Partial Gonadal Dysgenesis, CGD Complete Gonadal Dysgenesis, O/T Ovarian and Testicular Components, DG Dysgerminoma, GB Gondadoblastoma, - negative staining, + weakly positive, ++ strongly positive, C cytoplasm, N nuclei, T testicular tissue, O ovarian tissue