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Table 1 Characteristics of ONH cohort

From: Endocrine and pubertal disturbances in optic nerve hypoplasia, from infancy to adolescence

  % N
Gender   
   Female 58.4 59/101
   Male 41.6 42/101
Referral Source a   
   Pediatrician 69.3 70/101
   Ophthalmologist 14.9 15/101
   Neurologist 5.9 6/101
   Other 5.9 6/101
   Self-referral 2 2/101
   Unknown 2 2/101
Race/Ethnicity b   
   Caucasian 44.6 45/101
   Hispanic 24.8 25/101
   Native American 12.9 13/101
   Other 7 7/101
   Not documented 10.9 11/101
Laterality of ONH   
   Bilateral 74.3 75/101
   Unilateral 11.9 12/101
   Not documented 13.9 14/101
Brain Malformations c   
   Pituitary abnormalities 44.1 26/59
   Absence of septum pellucidum 46.8 36/77
   Corpus callosum hypoplasia 34.7 25/72
   Cortical dysplasia 16.9 14/83
   Schizencephaly 10.9 9/83
   Hydrocephalus 8.4 7/83
   Arachnoid cyst 6.0 5/83
Endocrinopathies d   
   Any endocrinopathy 72.3 73/101
   GH deficiency 62.0 57/92
   Hypothyroidism 54.0 54/100
   Adrenal insufficiency 51.1 47/92
   Diabetes insipidus 27.7 28/101
  1. aSome insurance plans only allow the primary pediatrician to order referrals.
  2. bBased on documentation in the medical record.
  3. cTotal number of subjects varies based on available MRI reports.
  4. dTotal number of subjects varies based on available lab results.