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Table 1 Clinical manifestation of SOD patients

From: A multicenter study of endocrine abnormalities in septo-optic dysplasia (SOD) in Asean countries

Clinical manifestation   Clinical manifestation  
Age at presentation (months) mean ± SD 33 ± 39 months (range 20 - 178) MRI findings Absence of septum pellucidum(%) 62
Ht SDS, mean ± SD -0.97 ± 1.97   Pituitary hypoplasia (%) 33
Wt SDS, mean ± SD 0.02 ± 2.35   Abnormal of corpus callosum (%) 16
Eye presentation Nystagmus (%) 54   Cortical dysplasia (%) 8
  Squint (%) 3 Endocrine abnormalities Hypothyroid (%) 35
  Poor vision (%) 35   GH insufficiency (%) 29
Delayed development (%) 16.2   Delayed/arrested puberty/suspected HG (%) 23
Seizure (%) 7.9   Cortical insufficiency (%) 17
Hypoglycemia (%) 8.1   Diabetes insipidus (%) 19
Neonatal jaundice (%) 2.7 Eye examination Unilat ON hypoplasia 13
Undescended testes (%) (boys) 5.4   Bilat ON hypoplasia 84
Micropenis (%) (boys) 21   Microcornea 3
  1. HG = Hypogonadism, ON = Optic nerve