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Table 4 Protein spot displaying intensity differences (p < 0.05) in pros-OB group after 2 SDS-BMI reduction

From: Proteomic analysis allows for early detection of potential markers of metabolic impairment in very young obese children

Spot

Spot intensity after weight loss

MS

MS

MS

MS-MS

MS-MS

MS-MS

Identification

Significance level

Score/Cut.off

Matched fragments

Sequence coverage

Score/Cut-off

Matched fragments

Sequence coverage

1704

Downregulated, p < 0.05

126/66

18

64

114/40

10(5)

37

Alpha-1-Antitrypsin

2201

Upregulated, p < 0.01

44/66

3

--

91/41

2(2)

12

Apolipoprotein A1

4801

Downregulated, p < 0.01

90/66

8

25

88/59

4(1)

12

Alpha-1B-glycoprotein

5103

Upregulated, p < 0.05

117/66

8

87

159/57

5(2)

79

Transthyretin

5503

Upregulated, p < 0.05

56/66

6

--

81/59

2(0)

4

Haptoglobin

7201

Upregulated, p < 0.01

106/66

16

66

76/59

3(2)

13

Apolipoprotein A1

7501

Upregulated, p < 0.05

55/66

4

--

86/59

2(2)

4

Haptoglobin

9101

Downregulated, p < 0.05

49/66

3

--

105/55

1(1)

4

Haptoglobin

  1. The second column shows the direction of the change observed after weight loss. Abbreviations: MS Mass spectrometry, MS-MS Tandem mass spectrometry.