CPP | EP | p value | |
---|---|---|---|
n | 37 | 34 | - |
Treated/Untreated | 29/8 | 14/20 | - |
Clinical characteristics | - | ||
Chronological age (yr) | 7.4 ± 1.3 | 8.8 ± 0.6 | 0.001 |
Bone age (yr) | 8.7 ± 2.1 | 9.3 ± 1.3 | NS |
Weight (Kg) | 32.1 ± 6.7 | 32.6 ± 4.4 | NS |
Weight (z-score) | 1.4 ± 0.8 | 1.9 ± 1.2 | 0.001 |
Height (SDS) | 2.8 ± 1.2 | 1.3 ± 1.1 | 0.001 |
BMI (Kg/m2) | 18.8 ± 2.4 | 18.2 ± 2 | NS |
BMI (z-score) | 1.1 ± 0.8 | 0.6 ± 0.7 | 0.004 |
Obesity/Overweight n(%) | 27 (72.9) | 12 (35.3) | 0.001 |
Obesity n(%) | 9 (24.3) | 3 (8.8) | NS |
Overweight n(%) | 18 (48.6) | 9 (26.5) | 0.054 |
Predict adult height (SDS) (SDS) (SDS) | 0.3 ± 2.3 | 1.5 ± 1.2 | 0.04 |
Height velocity (SDS) | 1.6 ± 2.1 | 1.8 ± 1.8 | NS |
Hormonal evaluation | |||
DHEAS (ng/ml) | 51.1 ± 34.2 | 52.8 ± 23.7 | NS |
LH peak (IU/L) | 10.9 ± 7.3 | 6.1 ± 4.5 | 0.01 |
LH to FSH stimulated ratio | 1.1 ± 0.7 | 1.1 ± 1.7 | NS |
Estradiol (pg/ml) | 22.3 ± 17 | 14 ± 11.8 | 0.01 |
Ovarian volume (ml) | 1.7 ± 0.7 | 1.8 ± 0.5 | NS |
Uterine length (cm) | 3.7 ± 1.2 | 3.4 ± 1 | NS |
Metabolic profile | |||
Fasting glucose (mg/dl) | 73.3 ± 8.5 | 80.2 ± 10.2 | 0.04 |
Total Cholesterol (mg/dl) | 158.6 ± 31.9 | 185.6 ± 35.7 | 0.02 |
LDL-C (mg/dl) | 97 ± 35.1 | 113.2 ± 17.6 | NS |
HDL-C (mg/dl) | 45 ± 8.9 | 53 ± 9.1 | NS |
TGR (mg/dl) | 89.8 ± 46.7 | 104.8 ± 48.8 | NS |
TGR/HDL-C ratio | 2.2 ± 0.9 | 1.5 ± 0.5 | NS |