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Table 9 Comparison of Our Results with Published Adult Heights of Controls & Treated Children

From: Growth hormone significantly increases the adult height of children with idiopathic short stature: comparison of subgroups and benefit

  AH Controls #305 AH Treated #212 Difference Benefit
Published Study [Ref. #] Number mg/kg/wk Mean SDS Mean SDS Mean SDS Males cm Females cm
Lopez-Siguero et al. [4] 35 0.16 to 0.25 -2.03 -1.31 0.72 4.86 NA
Coutant et al. [5] 32 0.16 -2.08 -2.10 -0.02 -0.13 -0.12
Lopez-Siguero et al. [6] 20 0.16 to 0.25 -2.01 -1.46 0.55 3.71 NA
Leschek et al.* [1] 22 0.22 -2.34 -1.77 0.57 3.84 3.50
Hindmarsh et al. [7] 16 0.16 to 0.28 -1.88 -1.33 0.55 3.71 3.38
Buchlis et al. [8] 36 0.3 -2.10 -1.50 0.60 0.4 M 1.2 F 3.00 6.8
Albertsson-Wikland et al.* [3] 31 0.47 -2.20 -1.50 0.70 5.0 4.30
McCaughey et al.* [2] 8 0.35 0.4 to 0.31 -2.37 -1.14 1.23 NA 7.55
Wit et al. [9] 12 0.32 0.32 to 0.26 -2.40 -1.30 1.10 7.42 6.75
Total number 212       
Mean 23.6   -2.16 -1.49 0.67 3.92 4.83
Minimum 8   -2.40 -2.10 -0.02 -0.13 -0.12
Maximum 36   -1.88 -1.14 1.23 7.42 7.55
Our study treated 88 0.32 (0.03) (-2.16) (Historical) -0.71 1.45 9.8 8.9
Difference        
Mean     +0.78 +0.78 5.2 4.8
Minimum     +0.43 +0.22 1.5 1.35
Maximum     +1.39 +1.47 9.9 9.0
  1. *Randomized controlled trials; M = male; F = Female.