Mean (SD) [min to max] | Number | Treatment start age (yrs) | Stop age (yrs) | Baseline height SDS (SD) | Adult height SDS (SD) | Adult height gain SDS (SD) |
---|---|---|---|---|---|---|
Males – NFSS | ||||||
Normal puberty | 20 | 8.6 (2.76) [5.0 to 13.4] | 16.4 (0.97) [14.7 to 18.3] | -2.53 (0.47) [-3.76 to -1.98] | -0.60 (0.67) [-1.73 to 0.81] | 1.94 (0.60) [0.94 to 3.01] |
Delayed puberty | 27 | 14.4 (1.10) [12.4 to 16.3] | 17.9 (0.84) [16.0 to 19.4] | -2.60 (0.34) [-3.37 to -2.00] | -0.49 (0.61) [-1.36 to 1.13] | 2.11 (0.66) [1.30 to 3.91] |
 |  | p <0.001 |  | p, 0.601 | p, 0.603 | p, 0.372 |
Males – FSS | ||||||
Normal puberty | 12 | 10.3 (2.47) [4.7 to 13.7] | 16.9 (0.77) [15.7 to 18.1] | -2.65 (0.83) [-4.51 to -1.98] | -1.19 (0.79) [-2.20 to 0.22] | 1.46 (0.68) [0.29 to 2.40] |
Delayed puberty | 9 | 14.1 (1.31) [11.6 to 15.9] | 17.6 (0.65) [16.9 to 18.7] | -2.51 (0.49) [-3.26 to -1.96] | -1.07 (0.62) [-2.20 to 0.24] | 1.44 (0.52) [0.86 to 2.20] |
 |  | p <0.001 |  | p, 0.669 | p, 0.729 | p, 0.949 |
Females – NFSS | ||||||
Normal puberty | 13 | 11.4 (1.21) [9.6 to 13.3] | 15.5 (0.81) [13.5 to 16.7] | -2.80 (1.04) [-5.20 to -1.81] | -0.77 (0.57) [-1.84 to 0.09] | 2.03 (0.88) [1.04 to 4.13] |