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Table 2 All ISS (NFSS and FSS) SDS

From: Growth hormone significantly increases the adult height of children with idiopathic short stature: comparison of subgroups and benefit

Males & Females mean SDS (SD) Treated with GH
Number 88
 Baseline Height (Base H) -2.61 (0.62)
 MPH -0.65 (0.92)
 AH (or Near) -0.71 (0.74)
 AH Gain SDS (AH – Base H) +1.90 (0.76)
Males mean SDS (SD) Total Normal puberty Delayed puberty NP to DP
Number 68 32 36 p value
 Base H -2.58 (0.52) -2.58 (0.63) -2.58 (0.38) NS 0.977
 MPH -0.78 (0.84) -0.94 (0.86) -0.63 (0.79) NS 0.141
 Fa H. -0.44 (0.90) -0.49 (0.96) -0.39 (0.84) NS 0.653
 AH (or Near) -0.72 (0.72) -0.82 (0.77) -0.64 (0.66) NS 0.319
 AH Gain SDS (AH – Base H) +1.86 (0.69) +1.76 (0.67) +1.94 (0.69) NS 0.280
Females mean SDS (SD) Total Normal puberty Delayed puberty NP to DP
Number 20 17 3 p value
 Base H -2.71 (0.96) -2.75 (0.93) -2.48 (0.44) NS 0.484
 MPH -0.18 (0.85) -0.23 (1.08) +0.09 (0.62) NS 0.851
 Mo H. -0.57 (0.62) -0.60 (0.80) -0.39 (0.94) NS 0.953
 AH (or Near) -0.65 (0.70) -0.77 (0.72) -0.02 (0.82) NS 0.300
 AH Gain SDS (AH – Base H) +2.06 (0.97) +1.98 (0.87) +2.50 (1.23) NS 0.647
Males with Non-familial Short Stature (NFSS)
Mean SDS (SD) Total Normal puberty Delayed puberty NP to DP
Number 47 20 27 p value
 Base H -2.57 (0.41) -2.53 (0.47) -2.60 (0.34) NS 0.601
 MPH -0.44 (0.73) -0.58 (0.80) -0.32 (0.65) NS 0.262
 Fa H -0.18 (0.76) -0.22 (0.89) -0.15 (0.64) NS 0.758
 AH (or Near) -0.54 (0.64) -0.60 (0.67) -0.49 (0.61) NS 0.603
 AH Gain SDS (AH – Base H) +2.04 (0.64) +1.94 (0.60) +2.11 (0.66) NS 0.372
Males with Familial Short Stature (FSS)
Number 21 12 9 p value
 Base H -2.59 (0.71) -2.65 (0.83) -2.51 (0.49) NS 0.669
 MPH -1.52 (0.51) -1.54 (0.57) -1.49 (0.43) NS 0.835
 Fa H -0.99 (0.92) -0.94 (0.90) -1.06 (0.95) NS 0.779
 AH (or Near) -1.14 (0.72) -1.19 (0.79) -1.07 (0.62) NS 0.729
 AH Gain SDS (AH – Base H) +1.45 (0.62) +1.46 (0.68) +1.44 (0.52) NS 0.949
Females with Non-familial Short Stature (NFSS) NP to DP
Number 16 13 3 p value
 Base H -2.74 (0.96) -2.80 (1.04) -2.48 (0.44) NS 0.484
 MPH +0.15 (0.85) +0.16 (0.90) +0.09 (0.62) NS 0.851
 Mo H -0.35 (0.62) -0.34 (0.52) -0.39 (0.94) NS 0.953
 AH (or Near) -0.62 (0.70) -0.77 (0.57) -0.02 (0.82) NS 0.300
 AH Gain SDS (AH – Base H) +2.12 (0.97) +2.03 (0.88) +2.50 (1.23) NS 0.647
Females with Familial Short Stature (FSS)  
 Number 4 4 0  
 Base H -2.59 (0.33) -2.59 (0.33)   
 MPH -1.49 (0.45) -1.49 (0.45)   
 Mo H -1.43 (0.97) -1.43 (0.97)   
 AH (or Near) -0.78 (1.07) -0.78 (1.07)   
 AH Gain SDS (AH – Base H) 1.81 (0.80) 1.81 (0.80)