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Table 2 All ISS (NFSS and FSS) SDS

From: Growth hormone significantly increases the adult height of children with idiopathic short stature: comparison of subgroups and benefit

Males & Females mean SDS (SD)

Treated with GH

Number

88

 Baseline Height (Base H)

-2.61 (0.62)

 MPH

-0.65 (0.92)

 AH (or Near)

-0.71 (0.74)

 AH Gain SDS (AH – Base H)

+1.90 (0.76)

Males mean SDS (SD)

Total

Normal puberty

Delayed puberty

NP to DP

Number

68

32

36

p value

 Base H

-2.58 (0.52)

-2.58 (0.63)

-2.58 (0.38)

NS 0.977

 MPH

-0.78 (0.84)

-0.94 (0.86)

-0.63 (0.79)

NS 0.141

 Fa H.

-0.44 (0.90)

-0.49 (0.96)

-0.39 (0.84)

NS 0.653

 AH (or Near)

-0.72 (0.72)

-0.82 (0.77)

-0.64 (0.66)

NS 0.319

 AH Gain SDS (AH – Base H)

+1.86 (0.69)

+1.76 (0.67)

+1.94 (0.69)

NS 0.280

Females mean SDS (SD)

Total

Normal puberty

Delayed puberty

NP to DP

Number

20

17

3

p value

 Base H

-2.71 (0.96)

-2.75 (0.93)

-2.48 (0.44)

NS 0.484

 MPH

-0.18 (0.85)

-0.23 (1.08)

+0.09 (0.62)

NS 0.851

 Mo H.

-0.57 (0.62)

-0.60 (0.80)

-0.39 (0.94)

NS 0.953

 AH (or Near)

-0.65 (0.70)

-0.77 (0.72)

-0.02 (0.82)

NS 0.300

 AH Gain SDS (AH – Base H)

+2.06 (0.97)

+1.98 (0.87)

+2.50 (1.23)

NS 0.647

Males with Non-familial Short Stature (NFSS)

Mean SDS (SD)

Total

Normal puberty

Delayed puberty

NP to DP

Number

47

20

27

p value

 Base H

-2.57 (0.41)

-2.53 (0.47)

-2.60 (0.34)

NS 0.601

 MPH

-0.44 (0.73)

-0.58 (0.80)

-0.32 (0.65)

NS 0.262

 Fa H

-0.18 (0.76)

-0.22 (0.89)

-0.15 (0.64)

NS 0.758

 AH (or Near)

-0.54 (0.64)

-0.60 (0.67)

-0.49 (0.61)

NS 0.603

 AH Gain SDS (AH – Base H)

+2.04 (0.64)

+1.94 (0.60)

+2.11 (0.66)

NS 0.372

Males with Familial Short Stature (FSS)

Number

21

12

9

p value

 Base H

-2.59 (0.71)

-2.65 (0.83)

-2.51 (0.49)

NS 0.669

 MPH

-1.52 (0.51)

-1.54 (0.57)

-1.49 (0.43)

NS 0.835

 Fa H

-0.99 (0.92)

-0.94 (0.90)

-1.06 (0.95)

NS 0.779

 AH (or Near)

-1.14 (0.72)

-1.19 (0.79)

-1.07 (0.62)

NS 0.729

 AH Gain SDS (AH – Base H)

+1.45 (0.62)

+1.46 (0.68)

+1.44 (0.52)

NS 0.949

Females with Non-familial Short Stature (NFSS)

NP to DP

Number

16

13

3

p value

 Base H

-2.74 (0.96)

-2.80 (1.04)

-2.48 (0.44)

NS 0.484

 MPH

+0.15 (0.85)

+0.16 (0.90)

+0.09 (0.62)

NS 0.851

 Mo H

-0.35 (0.62)

-0.34 (0.52)

-0.39 (0.94)

NS 0.953

 AH (or Near)

-0.62 (0.70)

-0.77 (0.57)

-0.02 (0.82)

NS 0.300

 AH Gain SDS (AH – Base H)

+2.12 (0.97)

+2.03 (0.88)

+2.50 (1.23)

NS 0.647

Females with Familial Short Stature (FSS)

 

 Number

4

4

0

 

 Base H

-2.59 (0.33)

-2.59 (0.33)

  

 MPH

-1.49 (0.45)

-1.49 (0.45)

  

 Mo H

-1.43 (0.97)

-1.43 (0.97)

  

 AH (or Near)

-0.78 (1.07)

-0.78 (1.07)

  

 AH Gain SDS (AH – Base H)

1.81 (0.80)

1.81 (0.80)

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