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Table 1 Idiopathic short stature treated with GH, non-familial short stature (NFSS) & familial short stature (FSS)

From: Growth hormone significantly increases the adult height of children with idiopathic short stature: comparison of subgroups and benefit

 

NFSS Mean (SD)

FSS Mean (SD)

Reference mean (SD)

Characteristic

Males (#47)

Females (#16)

Males (#21)

Females (#4)

Normal

Age start – yr

11.96 (3.50)

12.08 (1.39)

11.96 (2.81)

12.07 (0.88)

 

BA start – yr

9.00 (3.20)

9.39 (1.51)

9.10 (2.91)

10.30 (1.38)

 

GH stim peak mean

12.4

10.8

13.1

14.8

>7 ng/ml

range – ng/ml

7.04 to 28.0

7.0 to 19.8

7.1 to 38.5

8.8 to 20.9

>7 ng/ml

GH Freq Samp 12 

2.53 (1.08) (#31)

 

2.49 (1.46) (#11)

 

M = 2.54 (0.84)

hr mean ng/ml

 

1.78 (0.64) (#8)

 

3.02 (#1)

F = 1.96 (0.85)

SMC – U/ml

0.79 (0.43) (#27)

0.87 (0.22) (#6)

1.09 (0.60) (#11)

1.55 (0.04) (#2)

T-I = 1.04 (0.66)

IGF-1 – ng/ml

144 (101) (#19)

166 (63) (#10)

158 (69) (#11)

205 (9) (#2)

T-I = 109–485

T-II = 174-512

Duration Rx – yr

5.21 (2.69)

3.59 (0.94)

5.30 (2.30)

3.17 (0.88)

 
  1. Abbreviations: GH serum growth hormone, BA bone age, (#) number, M males, F females, T Tanner stage.