Table 2 GH Research Society Consensus Guidelines [10]^*, criteria for investigations of the GH-IGF axis

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Severe short stature, height < -3 SDS

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Height <1.5 SDS below midparental target height

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Height < -2 SDS AND height velocity < -1 SDS for chronological age for >1 year; decrease in height SDS of >0.5 SDS over 1 year (children >2 years)

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Height velocity < -2 SDS for >1 year, or height velocity < -1.5 SDS for 2 years

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Signs indicative of an intracranial lesion

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Signs of multiple pituitary hormone deficiency

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Neonatal signs and symptoms of GH deficiency