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Table 2 GH Research Society Consensus Guidelines [10]*, criteria for investigations of the GH-IGF axis

From: Towards identification of molecular mechanisms of short stature

Severe short stature, height < -3 SDS
Height <1.5 SDS below midparental target height
Height < -2 SDS AND height velocity < -1 SDS for chronological age for >1 year; decrease in height SDS of >0.5 SDS over 1 year (children >2 years)
Height velocity < -2 SDS for >1 year, or height velocity < -1.5 SDS for 2 years
Signs indicative of an intracranial lesion
Signs of multiple pituitary hormone deficiency
Neonatal signs and symptoms of GH deficiency
  1. *endorsed by the Councils and Drug and Therapeutics Committees of the European Society for Pediatric Endocrinology and the (formerly Lawson Wilkins) Pediatric Endocrine Society, the Australasian Pediatric Endocrinology Group, the Japanese Society for Pediatric Endocrinology, and the Sociedad Latinoamericana de Endocrinologia Pediatrica.