Table 1 Etiologies for short stature and common screening tests

Genetic short stature

Chromosomal aneuploidy, including Turner syndrome

Karyotype in girls

Microdeletion or duplication

Single gene disorders

Polygenic

Constitutional delay of growth and puberty

Hormonal pathologies

Growth hormone deficiency

IGF-1, IGF BP-3

Hypothyroidism

Thyroid function tests

Cushing syndrome

Systemic diseases

Inflammatory disease, e.g. IBD, JIA

erythrocyte sedimentation rate

Celiac disease

tissue transglutaminase antibodies

Renal disorders

electrolytes, creatinine

Liver disorders

liver function tests

Hematologic disorders

complete blood count

Birth history of IUGR/SGA

Medications