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Table 5 Serum lipid and carbohydrate data according to the parental origin of the retained X chromosome

From: Effect of the parental origin of the X-chromosome on the clinical features, associated complications, the two-year-response to growth hormone (rhGH) and the biochemical profile in patients with turner syndrome

 

< 20 years (n =  67)

≥ 20 years (n =  48)

Xm (n =  48)

Xp (n =  19)

P

Xm (n =  32)

Xp (n =  16)

p

Total cholesterol (mmol/l)

175 ± 29

183 ± 35

0.21

199 ± 38

181 ± 41

0.03

HDL-cholesterol (mmol/l)

61 ± 15

62 ± 13

0.76

55 ± 11

61 ± 15

0.13

LDL-cholesterol (mmol/l)

98 ± 21

101 ± 15

0.65

105 ± 17

95 ± 21

0.04

Triglycerides (mmol/l)

95 ± 52

97 ± 45

0.61

127 ± 55

99 ± 52

0.001

Fasting glucose (mg/dl)

81 ± 9

85 ± 9

0.18

91 ± 8

88 ± 10

0.38

BMI

19.9 ± 1.34

20.7 ± 2.13

0.54

25.1 ± 7.3

24.7 ± 6.1

0.81

  1. The means of Xm and Xp were compared by one-way ANCOVA analysis to age and BMI used as covariates, followed by Tukey’s significant-difference test. Two-sided p values were calculated for age, BMI, total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides and fasting glucose, but were found to be significantly different only for total cholesterol (p ≤ 0.001), and for LDL cholesterol (p ≤ 0.037) in the ≥ 20-year-group.
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International Journal of Pediatric Endocrinology

ISSN: 1687-9856

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